Structural homology of HHV-6B epitopes as candidates for molecular mimicry triggers of the onset type one diabetes mellitus [PDF]
Oxf Open ImmunolObjectives To study whether HHV-6B can act as a molecular mimic to trigger onset of Type One Diabetes Mellitus (T1DM) by assessing structural and binding similarities between HHV-6B derived epitopes and T1DM autoantigen derived epitopes.
McKay Jones, Julio Facelli
semanticscholar +2 more sources
Retraction to: A complex evolutionary relationship between HHV-6A and HHV-6B. [PDF]
Virus Evol, 2019 [This retracts the article DOI: 10.1093/ve/vez043.].
Forni D +4 more
europepmc +4 more sources
A Viral–Host Immunogenetic Interaction Model in Hodgkin Lymphoma: Co-Association of HHV-6B Infection and IL-18 rs1946518 Polymorphism [PDF]
Asian Pac J Cancer PrevBackground: Hodgkin lymphoma (HL) arises from germinal center B cells through complex viral, genetic, and environmental factors. This study examines HHV-6B infection and the IL-18 rs1946518 polymorphism as potential contributors to inflammation-driven HL
A. Alheany +3 more
semanticscholar +2 more sources
Identification of Two Competition‐Defined Neutralizing Antibody Groups Targeting the HHV‐6B gH/gL/gQ1/gQ2 Complex Independent of CD134 Binding [PDF]
Microbiol ImmunolHuman herpesvirus 6B (HHV‐6B) entry is mediated by the interaction between gH/gL/gQ1/gQ2 complex (tetramer) and CD134 expressed on activated T cells. In this study, we identified and characterized a panel of monoclonal antibodies targeting the HHV‐6B ...
Achmad Januar Er Putra +6 more
semanticscholar +2 more sources
Corrigendum: Structural Models for Roseolovirus U20 And U21: Non-Classical MHC-I Like Proteins From HHV-6A, HHV-6B, and HHV-7 [PDF]
Front Immunol, 2022 [This corrects the article DOI: 10.3389/fimmu.2022.864898.].
Grant C Weaver +4 more
semanticscholar +2 more sources
Detection of HHV-5 HHV-6a HHV-6b and HHV-7 in the urine: potential use as a non-invasive diagnostic tool for immune profiling [PDF]
Immun AgeingDecline in immune function with age has been studied extensively, but approaches to immune restoration have been hampered by the lack of simple methods of identifying individuals whose immune system is in decline.
S. Govind +16 more
semanticscholar +2 more sources
HHV-6A and HHV-6B in Autoimmune Disease
, 2014 A role for HHV-6 has been proposed in several autoimmune disorders (ADs), including multiple sclerosis (MS), autoimmune connective tissue diseases, and Hashimoto's thyroiditis. There are several potential mechanisms by which HHV-6 might induce autoimmune responses.
Francesco Broccolo, BROCCOLO, FRANCESCO
openaire +3 more sources
HHV-6B induces IFN-lambda1 responses in cord plasmacytoid dendritic cells through TLR9.
PLoS ONE, 2012 Human herpesvirus type 6B (HHV-6B) is a strong inducer of IFN-alpha and has the capacity to promote Th1 responses and block Th2 responses in vitro. In this study we addressed whether inactivated HHV-6B can also induce IFN lambda responses and to what ...
Inger Nordström, Kristina Eriksson
doaj +2 more sources
Evaluation of a method to measure HHV-6B infection in vitro based on cell size. [PDF]
Virol J, 2018 Human herpesvirus 6 (HHV-6A and HHV-6B) infection of cell cultures can be measured by different methods, including immunofluorescence microscopy, flow cytometry, or quantification of virus DNA by qPCR. These methods are reliable and sensitive but require long processing times and can be costly.
Becerra-Artiles A, Santoro T, Stern LJ.
europepmc +6 more sources
The clinical and epidemiological features of HHV-6A and HHV-6B infections in children of Moscow [PDF]
Детские инфекции (Москва), 2019 Human herpes virus type 6 (HHV-6) is the etiological agent of plenty diseases. The form of the developing pathology depends on the localization of the virus in T-lymphocytes and on virus type: HHV-6A or HHV-6B, but identification of the type is possible ...
M. Yu. Lysenkova +11 more
doaj +2 more sources