Evolutionary analysis of exogenous and integrated HHV-6A/HHV-6B populations [PDF]
Virus Evol, 2020 Human betaherpesviruses 6A and 6B (HHV-6A and HHV-6B) are highly prevalent in human populations. The genomes of these viruses can be stably integrated at the telomeres of human chromosomes and be vertically transmitted (inherited chromosomally integrated
D. Forni +4 more
semanticscholar +8 more sources
Characterization of the HHV-6B U20 Immunoevasin [PDF]
J Virol, 2023 The roseolovirus U20 proteins are virus-encoded integral membrane glycoproteins possessing class I major histocompatibility complex (MHC)-like folds.
C. L. Schneider +3 more
semanticscholar +4 more sources
Classification of HHV-6A and HHV-6B as distinct viruses. [PDF]
Arch Virol, 2014 Shortly after the discovery of human herpesvirus 6 (HHV-6), two distinct variants, HHV-6A and HHV-6B, were identified. In 2012, the International Committee on Taxonomy of Viruses (ICTV) classified HHV-6A and HHV-6B as separate viruses. This review outlines several of the documented epidemiological, biological, and immunological distinctions between HHV-
Ablashi D +20 more
europepmc +8 more sources
A Sensitive Quantification of HHV-6B by Real-time PCR [PDF]
Biological Procedures Online, 2002 Human herpesvirus (HHV)-6B is a pathogen causing latent infection in virtually all humans. Nevertheless, the interaction of HHV-6B with its host cells is poorly understood. Although HHV-6B is approximately 90% homologous to HHV-6A, it expresses certain B-
Øster Bodil, Höllsberg Per
doaj +5 more sources
Uncovering the Cause of Pneumonia: Reactivation of HHV-6B in an Immunocompromised Patient [PDF]
Eur J Case Rep Intern MedHuman herpesvirus 6 (HHV-6) is a ubiquitous virus that commonly infects the paediatric population and establishes latency in the host following primary infection.
L. Rodrigues +4 more
semanticscholar +4 more sources
Outcomes of Haploidentical Stem Cell Transplant Recipients With HHV-6B Reactivation [PDF]
Open Forum Infect DisBackground Human herpesvirus 6B (HHV-6B) frequently reactivates following allogeneic stem cell transplant (alloHCT). Consensus guidelines note that haploidentical alloHCT may represent a high-risk population for which there is little evidence; this ...
Guy Handley +28 more
semanticscholar +4 more sources
HHV-6B ribonucleotide reductase sequesters NF-κB subunit p65 to inhibit innate immune responses [PDF]
iScienceSummary Human herpesvirus 6B (HHV-6B) belongs to the genus Roseolovirus of the betaherpesvirus subfamily, causing exanthema subitum and encephalitis.
Mansaku Hirai +5 more
semanticscholar +4 more sources
HHV-6B infection after umbilical cord blood stem cell transplantation with pruritus as the first symptom [PDF]
Acta Biochim Biophys Sin (Shanghai), 2023 Bone marrow hematopoietic stem cell transplantation (BMT) is one of the most effective treatments for hematological malignancies, and cord blood hematopoietic stem cell transplantation is one of them [1].
Bin Xu +8 more
semanticscholar +3 more sources
Oral Brincidofovir Decreased the Incidence of HHV-6B Viremia after Allogeneic HCT. [PDF]
Blood, 2020 Human herpesvirus 6B (HHV-6B) frequently reactivates after allogeneic hematopoietic cell transplantation (HCT). There are no randomized studies of antiviral treatments to prevent HHV-6B reactivation.
J. Hill +7 more
semanticscholar +4 more sources
Quantitative HHV-6B antigenemia test for the monitoring of transplant patients [PDF]
European Journal of Clinical Microbiology & Infectious Diseases, 2010 Human herpesvirus-6 (HHV-6) infection, mostly caused by variant B, is common after transplantation. Here, we report a new modified method using an HHV-6B glycoprotein IgG antibody, OHV-3, and attempt to quantify the HHV-6 antigenemia after liver transplantation.
Loginov, R. +4 more
core +5 more sources