A Sensitive Quantification of HHV-6B by Real-time PCR [PDF]
Human herpesvirus (HHV)-6B is a pathogen causing latent infection in virtually all humans. Nevertheless, the interaction of HHV-6B with its host cells is poorly understood. Although HHV-6B is approximately 90% homologous to HHV-6A, it expresses certain B-
Øster Bodil, Höllsberg Per
doaj +3 more sources
Characterization of the HHV-6B U20 Immunoevasin. [PDF]
The roseolovirus U20 proteins are virus-encoded integral membrane glycoproteins possessing class I major histocompatibility complex (MHC)-like folds. Surprisingly, although U20 proteins from HHV-6A and -6B share 92% identity, recent studies ascribe different functions to HHV6A U20 and HHV6B U20.
Schneider CL +3 more
europepmc +3 more sources
Persistent viremia in an immunocompetent patient with inherited chromosomally integrated HHV-6B. [PDF]
Human herpesvirus-6 (HHV-6), the virus which causes roseola, has traditionally been associated with benign and self-limited childhood illness. However, HHV-6 establishes lifelong latency and can reactivate in immunocompromised adult patients. In about 1% of cases, it integrates into the human genome as inherited chromosomally integrated HHV-6 (iciHHV-6)
Obeid M, Gakhal I, McDonald PJ.
europepmc +3 more sources
Clinical and epidemiological features of infections caused by HHV-6A and HHV-6B [PDF]
Objective. To determine the detection rates of HHV-6A and HHV-6B compared to other herpes viruses in children of different age groups. Materials and Methods.
Lysenkova M.Yu. +10 more
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HHV-6B infection after umbilical cord blood stem cell transplantation with pruritus as the first symptom. [PDF]
Xu B +8 more
europepmc +2 more sources
Uncovering the Cause of Pneumonia: Reactivation of HHV-6B in an Immunocompromised Patient. [PDF]
Human herpesvirus 6 (HHV-6) is a ubiquitous virus that commonly infects the paediatric population and establishes latency in the host following primary infection. As in other herpesviruses, HHV-6 may reactivate when the immune system becomes severely compromised, such as after chemotherapy or haematopoietic cell transplantation.
Rodrigues L +4 more
europepmc +3 more sources
Evolutionary analysis of exogenous and integrated HHV-6A/HHV-6B populations. [PDF]
AbstractHuman betaherpesviruses 6A and 6B (HHV-6A and HHV-6B) are highly prevalent in human populations. The genomes of these viruses can be stably integrated at the telomeres of human chromosomes and be vertically transmitted (inherited chromosomally integrated HHV-6A/HHV-6B, iciHHV-6A/iciHHV-6B).
Forni D +4 more
europepmc +5 more sources
Classification of HHV-6A and HHV-6B as distinct viruses. [PDF]
Shortly after the discovery of human herpesvirus 6 (HHV-6), two distinct variants, HHV-6A and HHV-6B, were identified. In 2012, the International Committee on Taxonomy of Viruses (ICTV) classified HHV-6A and HHV-6B as separate viruses. This review outlines several of the documented epidemiological, biological, and immunological distinctions between HHV-
Ablashi D +20 more
europepmc +6 more sources
Human Herpesvirus 6B U26 Inhibits the Activation of the RLR/MAVS Signaling Pathway
HHV-6B (human herpesvirus 6B) is well known to evade host antiviral responses and establish a lifelong latent infection. How HHV-6B evades RNA recognition is still poorly understood.
Xuefeng Jiang +14 more
doaj +1 more source
Role of HHV-6B Infection in Mesial Temporal Lobe Epilepsy. [PDF]
Investigators from Fujita Health University, Toyoake, and National Epilepsy Center, Shizuoka, Japan, studied the pathogenic role of HHV-6B in patients with mesial temporal lobe epilepsy (MTLE).
Millichap JJ, Millichap JG.
europepmc +6 more sources

