Results 51 to 60 of about 2,937 (141)

Viral Immunity in Immunoglobulin Products: Global Immunity Debt and Autoimmunity in the Postpandemic Era

European Journal of Immunology, Volume 56, Issue 3, March 2026.
Immunoglobulin products derived from pooled global plasma reflect population‐level antiviral immunity. Analysis of batches from 2017 to 2023 reveals pandemic‐driven shifts in viral antibody profiles and a concurrent rise in autoantibodies, notably against TRIM21/Ro52, highlighting links between SARS‐CoV‐2, immunity debt, and autoimmunity.
Hannes Lindahl, Katy Shaw‐Saliba, H. Benjamin Larman, C. I. Edvard Smith, Peter Bergman   +4 more
wiley   +1 more source

The Promyelocytic Leukemia Protein facilitates human herpesvirus 6B chromosomal integration, immediate-early 1 protein multiSUMOylation and its localization at telomeres.

PLoS Pathogens, 2020
Human herpesvirus 6B (HHV-6B) is a betaherpesvirus capable of integrating its genome into the telomeres of host chromosomes. Until now, the cellular and/or viral proteins facilitating HHV-6B integration have remained elusive. Here we show that a cellular
Vanessa Collin, Annie Gravel, Benedikt B Kaufer, Louis Flamand   +3 more
doaj   +1 more source

Molecular Engineering for Enhanced Second‐Order Nonlinear Response in Spontaneously‐Oriented Evaporated Organic Films

Advanced Optical Materials, Volume 14, Issue 7, 16 February 2026.
Intramolecular bridge‐locking frustrates detrimental anti‐parallel packing in evaporated organic films. This design enhances net polar orientation, leading to a twofold off‐resonance increase in the second‐order nonlinear susceptibility (χ(2)) without electric‐field poling.
Pierre‐Luc Thériault, Heorhii V. Humeniuk, Zhechang He, Gabriel Juteau, Alexandre Malinge, Dmytro F. Perepichka, Stéphane Kéna‐Cohen   +6 more
wiley   +1 more source

Metagenomic Next-Generation Sequencing (mNGS) of cerebrospinal fluid for diagnosis of human herpesvirus 6B encephalitis following transplantation for severe aplastic anemia

Journal of Infection in Developing Countries
Introduction: Human herpesvirus 6B (HHV-6B) encephalitis is common in immunosuppressed patients and presents a diagnostic challenge for physicians.
Kaile Zhang, Jianli Xu, Gang Chen, Ruixue Yang, Ming Jiang, Hailong Yuan   +5 more
doaj   +1 more source

The Telomeric Repeats of Human Herpesvirus 6A (HHV-6A) Are Required for Efficient Virus Integration. [PDF]

PLoS Pathogens, 2016
Human herpesvirus 6A (HHV-6A) and 6B (HHV-6B) are ubiquitous betaherpesviruses that infects humans within the first years of life and establishes latency in various cell types.
Nina Wallaschek, Anirban Sanyal, Fabian Pirzer, Annie Gravel, Yasuko Mori, Louis Flamand, Benedikt B Kaufer   +6 more
doaj   +1 more source

Direct Repeat 6 from human herpesvirus-6B encodes a nuclear protein that forms a complex with the viral DNA processivity factor p41. [PDF]

PLoS ONE, 2009
The SalI-L fragment from human herpesvirus 6A (HHV-6A) encodes a protein DR7 that has been reported to produce fibrosarcomas when injected into nude mice, to transform NIH3T3 cells, and to interact with and inhibit the function of p53.
Mariane H Schleimann, Janni M L Møller, Emil Kofod-Olsen, Per Höllsberg   +3 more
doaj   +1 more source

Epstein‐Barr Virus Infection at Single‐Cell Resolution

Journal of Medical Virology, Volume 98, Issue 2, February 2026.
ABSTRACT Epstein‐Barr virus (EBV) infection has been studied at single‐cell resolution for six decades and counting. Such investigations can reveal virus‐host interactions and their dependence on viral strain, cellular niche, infection program, immune response regulation, and time.
Elliott D. SoRelle
wiley   +1 more source

Active HHV-6 Infection of Cerebellar Purkinje Cells in Mood Disorders

Frontiers in Microbiology, 2018
Early-life infections and associated neuroinflammation is incriminated in the pathogenesis of various mood disorders. Infection with human roseoloviruses, HHV-6A and HHV-6B, allows viral latency in the central nervous system and other tissues, which can ...
Bhupesh K. Prusty, Bhupesh K. Prusty, Nitish Gulve, Sheila Govind, Gerhard R. F. Krueger, Julia Feichtinger, Julia Feichtinger, Lee Larcombe, Richard Aspinall, Dharam V. Ablashi, Carla T. Toro, Carla T. Toro   +11 more
doaj   +1 more source

Long-term outcome in corneal endotheliitis with molecular detection of herpes simplex virus 1 and human herpes virus 6: a case report

BMC Ophthalmology, 2022
Background Human herpesvirus 6B (HHV-6B) is known to cause exanthema subitem and has been detected in various ocular diseases, including keratitis, uveitis, optic neuritis, and endophthalmitis; however, the long-term outcome after the reactivation of HHV-
Takashi Ono, Takuya Iwasaki, Yukiko Terada, Yosai Mori, Ryohei Nejima, Mineo Ozaki, Manabu Mochizuki, Kazunori Miyata   +7 more
doaj   +1 more source

The interacting etiologies of hippocampal sclerosis in epilepsy: A scoping review

Epilepsia, Volume 67, Issue 2, Page 527-541, February 2026.
Abstract According to the International League Against Epilepsy classification, mesial temporal lobe epilepsy with hippocampal sclerosis (MTLE‐HS) is considered an epilepsy syndrome. Several etiologies may precede HS, but there is little overview in the literature about these etiologies.
Boris Deleu, Jules Jeuris, Wim Van Paesschen   +2 more
wiley   +1 more source