From 2D to 4D: a containerized workflow and browser to explore dynamic chromatin architecture. [PDF]
Rogers DH +7 more
europepmc +1 more source
This study identifies TOPK as a dual‐function target in gastric cancer: it drives tumor cell proliferation and migration, and under IFN‐γ stimulation, phosphorylates eIF4F complex component eIF4A1 to enhance STAT1 mRNA translation, thereby promoting PD‐L1/IDO1‐mediated tumor immunometabolic evasion.
Junbing Chen +16 more
wiley +1 more source
MicroRNA210 regulated brain pericyte dysfunction exacerbates hypoxic-ischemic brain injury in neonatal mice. [PDF]
Hu S +8 more
europepmc +1 more source
Compartmentalized Homeostasis Drives High Bamboo Forest Productivity under Nutrient Imbalance
This study reveals how Moso bamboo achieves high productivity despite nutrient‐poor soils. It employs a unique strategy, maintaining strict nutrient balance in its leaves while using woody tissues as flexible storage reservoirs. This compartmentalized mechanism buffers the plant from soil phosphorus limitation and microbial competition, resolving the ...
Zhikang Wang +13 more
wiley +1 more source
Evaluation of Passive Air Sampling for Monitoring Current-Use Pesticide Pollution near Large-Scale Banana Plantations in Costa Rica. [PDF]
Solano Díaz K +5 more
europepmc +1 more source
NanoLoop: A Deep Learning Framework Leveraging Nanopore Sequencing for Chromatin Loop Prediction
Chromatin loops are central to gene regulation and 3D genome organization. Leveraging Nanopore sequencing's ability to jointly capture DNA sequence and methylation, we present NanoLoop, the first framework for genome‐wide chromatin loop prediction using Nanopore data.
Wenjie Huang +5 more
wiley +1 more source
Temporal and Spatial Gene Expression Dynamics in Neonatal HI Hippocampus with Focus on Arginase. [PDF]
Smith MA +11 more
europepmc +1 more source
His‐MMDM: Multi‐Domain and Multi‐Omics Translation of Histopathological Images with Diffusion Models
His‐MMDM is a diffusion model‐based framework for scalable multi‐domain and multi‐omics translation of histopathological images, enabling tasks from virtual staining, cross‐tumor knowledge transfer, and omics‐guided image editing. ABSTRACT Generative AI (GenAI) has advanced computational pathology through various image translation models.
Zhongxiao Li +13 more
wiley +1 more source
<i>Lactobacillus gasseri</i> CBT LGA2 alleviates muscle protein degradation and inflammation in immobilization-induced mouse. [PDF]
Jang JH, Lim SJ, Choi HS, Lim S, Oh NS.
europepmc +1 more source

