Results 141 to 150 of about 2,360,372 (228)

Architected Inverse Nacre Hydrogels With High Strength and Crack‐Insensitive Toughness

Advanced Science, EarlyView.
Hydrogels hold promise for biomedical and engineering applications, yet their practical use is fundamentally limited by the strength‐toughness trade‐off and poor fatigue resistance. In this study, a bioinspired inverse nacre architecture constructed via a scalable thermo‐calendering process is introduced, which overcomes these classic limitations ...
Haidi Wu, Qin Su, Cheng Guan, Biwang Pan, Wenjie Hu, Jun Yan, Yifan Feng, Longcheng Tang, Xuewu Huang, Jiefeng Gao, Wancheng Gu   +10 more
wiley   +1 more source

DeepExDC interprets genomic compartmentalization changes in single-cell Hi-C data. [PDF]

Brief Bioinform
Lyu H, Cao P, Long W, Yin X, Xu S, Fu L.
europepmc   +1 more source

scHiCDiff: detecting differential chromatin interactions in single-cell Hi-C data. [PDF]

Bioinformatics, 2023
Liu H, Ma W.
europepmc   +1 more source

Multi‐Omics Insights Into the Mechanisms of Early Muscle Fiber Difference and Transformation Between Lean‐Type and Chinese Indigenous Pigs

Advanced Science, EarlyView.
Multi‐omics analyses uncover breed‐specific cis‐regulatory landscapes and higher‐order chromatin architectural differences that underlie early postnatal muscle fiber divergence in pigs. A super‐enhancer upstream of PPP3CB recruits MEF2C to activate PPP3CB transcription, while the PPP3CB–MEF2C positive feedback loop promotes oxidative muscle fiber ...
Shuailong Zheng, Hainan Wu, Min Liu, Kunpeng Wu, Shuntao Huang, Zulfiqar Ahmed, Lenox Pius, Mengjin Zhu, Dequan Xu   +8 more
wiley   +1 more source

Unveiling Multi-Scale Architectural Features in Single-Cell Hi-C Data Using scCAFE. [PDF]

Adv Sci (Weinh)
Wang F, Lin J, Alinejad-Rokny H, Ma W, Meng L, Huang L, Yu J, Chen N, Wang Y, Yao Z, Xie W, Wong KC, Li X.   +12 more
europepmc   +1 more source

snHiC: a complete and simplified snakemake pipeline for grouped Hi-C data analysis. [PDF]

Bioinform Adv, 2023
Gregoricchio S, Zwart W.
europepmc   +1 more source

INB3P: A Multi‐Modal and Interpretable Co‐Attention Framework Integrating Property‐Aware Explanations and Memory‐Bank Contrastive Fusion for Blood–Brain Barrier Penetrating Peptide Discovery

Advanced Science, EarlyView.
INB3P is a multimodal framework for blood–brain barrier‐penetrating peptide prediction under extreme data scarcity and class imbalance. By combining physicochemical‐guided augmentation, sequence–structure co‐attention, and imbalance‐aware optimization, it improves predictive performance and interpretability.
Jingwei Lv, Qianyang Wu, Jian Liu, Binlu Yang, Yuanhao Li, Junlin Xu, Yajie Meng, Leyi Wei, Zilong Zhang, Quan Zou, Xiulai Li, Feifei Cui   +11 more
wiley   +1 more source

PB-DiffHiC: a statistical framework for detecting differential chromatin interactions from high resolution pseudo-bulk Hi-C data. [PDF]

BMC Genomics
Zhou Y, Hu Y, Tan L, Zhu J, Fei Y, Gu M, Tian D.   +6 more
europepmc   +1 more source

Magnetoelectric Nanoparticle‐Based Wireless Brain–Computer Interface: Underlying Physics and Projected Technology Pathway

Advanced Science, EarlyView.
Magnetoelectric nanoparticles (MENPs) enable fully wireless, minutely invasive neuromodulation, and potentially neural recording, by converting magnetic into electric and, conversely, electric into magnetic fields, respectively, at high spatiotemporal resolution.
Elric Zhang, Max Shotbolt, Mostafa Abdel‐Mottaleb, Shawnus Chen, Victoria Andre, Jieyuan Tian, Jonathan Shulgach, Max Murphy, Brian Noga, Ping Liang, Darcy Griffin, Douglas Weber, Marta Pardo, Salvador Pane, Sakhrat Khizroev   +14 more
wiley   +1 more source

A comprehensive review and benchmark of differential analysis tools for Hi-C data. [PDF]

Brief Bioinform
Jorge E, Foissac S, Neuvial P, Zytnicki M, Vialaneix N.   +4 more
europepmc   +1 more source