Results 151 to 160 of about 215,700 (227)

PB-DiffHiC: a statistical framework for detecting differential chromatin interactions from high resolution pseudo-bulk Hi-C data. [PDF]

BMC Genomics
Zhou Y, Hu Y, Tan L, Zhu J, Fei Y, Gu M, Tian D.   +6 more
europepmc   +1 more source

The shape of chromatin: insights from computational recognition of geometric patterns in Hi-C data. [PDF]

Brief Bioinform, 2023
Raffo A, Paulsen J.
europepmc   +1 more source

Ahcy Acts as an Effector of Hnf4a‐Driven Super‐Enhancer Activation to Alleviate MASLD During Intermittent Fasting

Advanced Science, EarlyView.
Our study identifies an Hnf4a‐driven super‐enhancer of hepatic Ahcy that mediates the protective effects of intermittent fasting against MASLD. Disruption of the Ahcy super‐enhancer reduces Ahcy expression and exacerbates lipid accumulation. This pathway prevents aberrant promoter hypermethylation by maintaining the SAM/SAH balance, as exemplified by ...
Huafeng Chen, Shilin Zhang, Xiaojie Deng, Wenqiang Xie, Fen Xu, Jie Shen, Hua Liang   +6 more
wiley   +1 more source

The first high-quality chromosome-level genome of Parupeneus biaculeatus using HiFi and Hi-C data. [PDF]

Sci Data
Luo Z, Yi M, Yang X, Luo Z, Li X, Jiang C, Kang B, Huang L, Lin HD, He X, Yan Y.   +10 more
europepmc   +1 more source

Single-cell Hi-C data enhancement with deep residual and generative adversarial networks. [PDF]

Bioinformatics, 2023
Wang Y, Guo Z, Cheng J.
europepmc   +1 more source

A Personalized Haplotype‐Resolved Near‐Gapless Genome Framework for Somatic Variant Discovery in Hepatocellular Carcinoma

Advanced Science, EarlyView.
A patient‐specific, haplotype‐resolved genome framework improves detection and interpretation of somatic variants in hepatocellular carcinoma. Using multi‐platform sequencing, the personalized assembly resolves complex regions including centromeres and MHC/HLA loci, enhances structural variant discovery, and links regulatory alterations to allele ...
Jiazheng Lin, Yao Xiao, Shuangzi Luo, Yifan Li, Wenfei Zhang, Xiaoyu Zhang, Xinyi Wang, Di Wu, Jieru Hong, Yongkun Luan, Xun Huang, Yixiu Wang, Ningbo Wu, Xiaoxiao Hu, Fei Zhao, Wei Li, Xiao Luo, Bi Shi   +17 more
wiley   +1 more source

Unicorn: enhancing single-cell Hi-C data with blind super-resolution for 3D genome structure reconstruction. [PDF]

Bioinformatics
Chandrashekar MKB, Menon R, Olowofila S, Oluwadare O.   +3 more
europepmc   +1 more source

Bending‐Stable Pressure Sensor Based on Natural Wood Nanofibers for Ultra‐Low Detection Limit

Advanced Science, EarlyView.
A wood nanofiber‐based flexible pressure sensor with intrinsic bending‐stable performance is developed through a porous electrospun architecture and interdigital electrode design. The device exhibits an ultra‐low detection limit and stable operation under deformation for physiological monitoring and spatial sensing, providing a sustainable strategy for
Xu Zeng, Zhengnan Sun, Yilin Wang, Yao Tan, Ranran Xu, Beomjoon Kim, Juergen Brugger, Xiaosheng Zhang   +7 more
wiley   +1 more source

Single‐Sensor Vibration Sensing in Anisotropic Composites Enabled by Disordered Metasurfaces

Advanced Science, EarlyView.
This work develops a single‐sensor vibration sensing (SSVS) framework that integrates disordered metasurfaces with compressive sensing. Comprehensive numerical and experimental validations demonstrate that, by manipulating anisotropic guided wave propagation through metasurfaces, the proposed SSVS framework enables high‐fidelity multi‐source vibration ...
Jianjie Zhang, Lanhe Xu, Zhongzheng Zhang, Yongbo Li, Eric Li, Asoke K. Nandi, Bing Li   +6 more
wiley   +1 more source

pC-SAC: A method for high-resolution 3D genome reconstruction from low-resolution Hi-C data. [PDF]

Nucleic Acids Res
Angel JC, El Amraoui N, Gürsoy G.
europepmc   +1 more source