Results 31 to 40 of about 73,109 (257)

A Statistical Algorithm of Disaggregating the Industrial Enterprise Restructuring Strategy [PDF]

open access: yesProblemi Ekonomiki, 2016
The aim of the article is to develop and test an algorithm of disaggregating the strategy plan for restructuring industrial enterprises within the concept of optimal planning based on the mathematical formulation of the problem of coordinating the ...
Kozyr-Chepurna Mariia A.   +1 more
doaj  

Time to Diagnosis Among Children and Adolescents With Cancer in Québec, Canada: A Population‐Based Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Timely cancer diagnosis in children and adolescents is important to improving outcomes. We aimed to quantify time to diagnosis and assess variations by patient, demographic and system‐level factors. Procedure We conducted a population‐based study of individuals aged 0–19 years diagnosed with one of 12 cancers from 2010 to 2022 in ...
Callum Mullen   +5 more
wiley   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo   +5 more
wiley   +1 more source

Research on urban comprehensive energy planning system based on hierarchical framework and CAS theory

open access: yesEnergy Reports, 2022
The innovation of the city’s integrated energy system has become the key to China’s realization of “carbon peaks by 2030 and carbon neutrality by 2060”.
Hao Huang   +4 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Hierarchical DDPG for Manipulator Motion Planning in Dynamic Environments

open access: yesAI, 2022
In this paper, a hierarchical reinforcement learning (HRL) architecture, namely a “Hierarchical Deep Deterministic Policy Gradient (HDDPG)” has been proposed and studied.
Dugan Um, Prasad Nethala, Hocheol Shin
doaj   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

Using Earley Parser for Verification of Totally Ordered Hierarchical Plans

open access: yesProceedings of the International Florida Artificial Intelligence Research Society Conference
Hierarchical planning extends classical planning by capturing the hierarchical structure of tasks via decomposition of tasks to subtasks. Hierarchical plan verification is the problem of determining whether a given plan is valid according to that ...
Kristýna Pantůčková   +2 more
doaj   +1 more source

Simple Hierarchical Planning with Diffusion

open access: yesCoRR
Diffusion-based generative methods have proven effective in modeling trajectories with offline datasets. However, they often face computational challenges and can falter in generalization, especially in capturing temporal abstractions for long-horizon tasks.
Chang Chen   +4 more
openaire   +3 more sources

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

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