Results 31 to 40 of about 34,892 (283)

Modulation of Perturbed Cardiac Metabolism in Rats Under High-Altitude Hypoxia by Combination Treatment With L-carnitine and Trimetazidine

open access: yesFrontiers in Physiology, 2021
High-altitude hypoxia has long been recognized as a vital etiology for high-altitude illnesses. High-altitude myocardial injury (HAMI) usually occurs in people who suffered from high-altitude exposure.
Hebing Xie   +5 more
doaj   +1 more source

Cerebral hemodynamic characteristics of acute mountain sickness upon acute high-altitude exposure at 3,700 m in young Chinese men. [PDF]

open access: yes, 2014
PURPOSE: We aimed at identifying the cerebral hemodynamic characteristics of acute mountain sickness (AMS). METHODS: Transcranial Doppler (TCD) sonography examinations were performed between 18 and 24 h after arrival at 3,700 m via plane from 500 m (n ...
Bian, Shi-Zhu   +8 more
core   +2 more sources

Human adaptation to high altitude: a review of convergence between genomic and proteomic signatures

open access: yesHuman Genomics, 2022
Both genomics- and proteomics-based investigations have identified several essential genes, proteins, and pathways that may facilitate human adaptive genotype/phenotype in a population-specific manner.
Vandana Sharma   +2 more
doaj   +1 more source

Internal sensations as a source of fear: exploring a link between hypoxia and flight phobia [PDF]

open access: yes, 2013
Although flight phobia is very common in the general population, knowledge of the underlying mechanisms is limited. The aim of the current study is to determine whether hypoxia is selectively associated with flight anxiety. We wanted to explore levels of
De Raedt, Rudi, Vanden Bogaerde, Anouk
core   +1 more source

Developmental responses to high altitude hypoxia [PDF]

open access: yesAmerican Journal of Physical Anthropology, 1970
AbstractFrom a review of published literature on developmental responses to high altitude, three major conclusions are derived. First, the small birth weight of high altitude native populations are adaptive responses to reduce the oxygen requirements, while the relative increase in the placental weight is a compromise mechanism to increase the volume ...
openaire   +3 more sources

Developmental adaptation to high altitude hypoxia [PDF]

open access: yesInternational Journal of Biometeorology, 1977
Experimental studies on animals and humans exposed to hypoxic stress have been reviewed. These data suggest that the influence of hypoxic stress, and the organism's response to it, are greater during growth than during adulthood. The organism's responses include alterations in the quantity and size of the alveolar units of the lungs, enlargement of the
openaire   +3 more sources

Protective effect of bioactive iridium nanozymes on high altitude-related hypoxia-induced kidney injury in mice

open access: yesFrontiers in Pharmacology, 2023
Introduction: High altitude-related hypoxia-induced organ damage significantly impacts people who are exposed to acute high-altitude environment. At present, kidney injury still lacks effective treatment strategies.
Yujing Wang   +6 more
doaj   +1 more source

Humans at high altitude: Hypoxia and fetal growth [PDF]

open access: yesRespiratory Physiology & Neurobiology, 2011
High-altitude studies offer insight into the evolutionary processes and physiological mechanisms affecting the early phases of the human lifespan. Chronic hypoxia slows fetal growth and reduces the pregnancy-associated rise in uterine artery (UA) blood flow. Multigenerational vs.
Lorna G, Moore   +2 more
openaire   +2 more sources

Physiological Genomics of Adaptation to High-Altitude Hypoxia

open access: yesAnnual Review of Animal Biosciences, 2021
Population genomic studies of humans and other animals at high altitude have generated many hypotheses about the genes and pathways that may have contributed to hypoxia adaptation. Future advances require experimental tests of such hypotheses to identify causal mechanisms.
Jay F, Storz, Zachary A, Cheviron
openaire   +3 more sources

Regulation of CYP450 and drug transporter mediated by gut microbiota under high-altitude hypoxia

open access: yesFrontiers in Pharmacology, 2022
Hypoxia, an essential feature of high-altitude environments, has a significant effect on drug metabolism. The hypoxia–gut microbiota–CYP450/drug transporter axis is emerging as a vital factor in drug metabolism.
Xue Bai   +9 more
doaj   +1 more source

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