Results 81 to 90 of about 34,892 (283)

Effects of altitude and exercise intensity on cardiac function in rats

Experimental Physiology
High‐altitude exercise affects cardiac function. This study investigated how altitude and exercise intensity interacted to affect cardiac function of Sprague‐Dawley rats.
Minxia Zhu, Xiaofeng Li, Bing Liu, Jing Guo, Yuanyuan Xiao, Zhiyao Liu, Mengru Duan, Yi Liu   +7 more
doaj   +1 more source

DATA in BRIEF of: Adaptative mechanisms indicated by placental protein expression changes in high-altitude Tibetan women during vaginal delivery

Data in Brief
Over a period of 30,000 to 40,000 years, high-altitude Tibetans have physiologically and genetically adapted to conditions such as hypoxia, low temperature, and high-intensity ultraviolet radiation.
Huifang Liu, Tana Wuren, Ri-li Ge
doaj   +1 more source

Regulation of High-Altitude Hypoxia on the Transcription of CYP450 and UGT1A1 Mediated by PXR and CAR

Frontiers in Pharmacology, 2020
Little is known about what roles the pregnane X receptor (PXR) and constitutive androstane receptor (CAR) play in drug metabolism in high-altitude hypoxia.
Ya-bin Duan, Ya-bin Duan, Jun-bo Zhu, Jun-bo Zhu, Jian-xin Yang, Gui-qin Liu, Xue Bai, Ning Qu, Xue-jun Wang, Xiang-yang Li   +9 more
doaj   +1 more source

High‐Altitude Adaptation of Frogs (Case Study: Nanorana parkeri): From Physiological Phenotypes to AltitudeOmics

Integrative Zoology, EarlyView.
High altitudes are challenging for the animals that inhabit these environments. The Xizang plateau frog (Nanorana parkeri) survives in high‐altitude environments through a synergistic strategy of metabolic remodeling and protein expression adjustment to optimize energy efficiency and enhance cellular protection.
Xuejing Zhang, Yonggang Niu, Shengkang Men, Yanghuilin Zhang, Xiaolong Tang, Kenneth B. Storey, Qiang Chen   +6 more
wiley   +1 more source

Thromboelastometry and Platelet Function during Acclimatization to High Altitude [PDF]

, 2018
Interaction between hypoxia and coagulation is important given the increased risk of thrombotic diseases in chronically hypoxic patients who reside at sea level and in residents at high altitude.
Baillie, J.K., Barber, M.T., Harrison, P., Horn, E.H., Jackson, A.I.R., MacInnis, M.J., Main, S.E., Moores, C., Nimmo, A.F., Paterson, G.G., Rocke, A.S., Schnopp, M.F., Stannett, C., Thompson, A.A.R.   +13 more
core   +3 more sources

Cenozoic Tectonics Ignite Mitochondrial Codon Innovations Propelling Canid Body Size Evolution and Transcontinental Radiations

Integrative Zoology, EarlyView.
We decode mitochondrial genomes across all extant canids, revealing lineage‐specific codon optimization driven by altitude, predation, and body size. A tripartite framework integrates geological events, metabolic constraints, and adaptive radiation to explain carnivore evolution.
Xiaoyang Wu, Xibao Wang, Yongquan Shang, Yao Chen, Haotian Cai, Tian Xia, Qinguo Wei, Weilai Sha, Honghai Zhang   +8 more
wiley   +1 more source

Effects of Hyperbaric Hypoxia on Some Enzyme Systems in the Mammalian Liver [PDF]

, 1978
The metabolic effects of hypobaric hypoxic stress on the mammalian liver were studied. The lactate dehydrogenase (LDH) and succinate dehydrogenase (SDH) activity of mouse liver homogenates were measured after exposure to an equivalent altitude of 36,000 ...
Baeyens, Dennis A., Meier, M. J.
core   +2 more sources

Risk factors for high-altitude headache upon acute high-altitude exposure at 3700 m in young Chinese men: a cohort study. [PDF]

, 2013
BackgroundThis prospective and observational study aimed to identify demographic, physiological and psychological risk factors associated with high-altitude headache (HAH) upon acute high-altitude exposure.MethodsEight hundred fifty subjects ascended by ...
Bian, Shi-Zhu, Chen, Guo-Zhu, Dong, Jun-Qing, Gao, Xu-Bin, Huang, Lan, Li, Ming, Liu, Xi, Yu, Jie, Zhang, Ji-Hang   +8 more
core   +2 more sources

Cardiovascular Response to High Altitude Hypoxia

Defence Science Journal, 1984
Normal and abnormal cardiovascular response to high altitude (HA) hypoxia were studied in 98 healthy subjects and in 15 patients with HA pulmonary oedema (HAPO) and acute mountain sickness (AMS) at an altitudeof 3,658 m. The healthy sea level (SL) residents showed marked blood volume changes during the first week with pulmonary hypotension and ...
openaire   +1 more source

Sustained high-altitude hypoxia increases cerebral oxygen metabolism

Journal of Applied Physiology, 2013
Acute mountain sickness (AMS) is a common condition occurring within hours of rapid exposure to high altitude. Despite its frequent occurrence, the pathophysiological mechanisms that underlie the condition remain poorly understood. We investigated the role of cerebral oxygen metabolism (CMRO2) in AMS.
Zachary M, Smith, Erin, Krizay, Jia, Guo, David D, Shin, Miriam, Scadeng, David J, Dubowitz   +5 more
openaire   +3 more sources