Results 21 to 30 of about 926,705 (358)

Functional deficits precede structural lesions in mice with high-fat diet-induced diabetic retinopathy [PDF]

open access: yes, 2016
Obesity predisposes to human type 2 diabetes, the most common cause of diabetic retinopathy. To determine if high-fat diet–induced diabetes in mice can model retinal disease, we weaned mice to chow or a high-fat diet and tested the hypothesis that diet ...
Bligard, Gregory W   +5 more
core   +2 more sources

Orlistat exerts anti-obesity and anti-tumorigenic effects in a transgenic mouse model of endometrial cancer

open access: yesFrontiers in Oncology, 2023
IntroductionAmong all cancers, endometrial cancer is most strongly associated with obesity, with more than 65% of endometrial cancers attributable to obesity and being overweight.
Guangxu Xu   +17 more
doaj   +1 more source

Vitamin D3 supplementation of a high fat high sugar diet ameliorates prediabetic phenotype in female LDLR–/–and LDLR+/+mice [PDF]

open access: yes, 2017
© 2017 The Authors. Immunity, Inflammation and Disease Published by John Wiley & Sons Ltd. INTRODUCTION: Fatty liver disease is prevalent in populations with high caloric intake.
Asai   +50 more
core   +1 more source

A high fat diet fosters elevated bisretinoids

open access: yesJournal of Biological Chemistry, 2023
High dietary fat intake is associated with metabolic dysregulation, but little is known regarding the effects of a high fat diet (HFD) on photoreceptor cell functioning. We explored the intersection of an HFD and the visual cycle adducts that form in photoreceptor cells by nonenzymatic reactions.
Kim, Hye Jin   +3 more
openaire   +2 more sources

Effects of Orlistat and herbal mixture extract on brain, testes functions and oxidative stress biomarkers in a rat model of high fat diet

open access: yesBeni-Suef University Journal of Basic and Applied Sciences, 2014
This study was designed to assess the effectiveness of herbal mixture extracts of pumpkin seed oil, peanuts shell and Orlistat on brain, testes functions, oxidative stress biomarkers and histopathological changes in male albino rats administered high fat
Sanaa R. Galaly   +3 more
doaj   +1 more source

High-Fat Diet Increases Bone Loss by Inducing Ferroptosis in Osteoblasts

open access: yesStem Cells International, 2022
Current research suggests that chronic high-fat dietary intake can lead to bone loss in adults; however, the mechanism by which high-fat diets affect the development of osteoporosis in individuals is unclear.
RunJiu Zhu   +8 more
doaj   +1 more source

Investigating A Dose Response Relationship between High Fat Diet Consumption and the Contractile Performance of Isolated Mouse Soleus, EDL and Diaphragm Muscles [PDF]

open access: yes, 2019
PurposeRecent evidence has demonstrated an obesity-induced, skeletal muscle-specific reduction in contractile performance. The extent and magnitude of these changes in relation to total dose of high-fat diet consumption remains unclear.
A Abdelmoula   +56 more
core   +1 more source

Maternal High-Fat Diet and Offspring Hypertension

open access: yesInternational Journal of Molecular Sciences, 2022
The incidence of hypertension has increased to epidemic levels in the past decades. Increasing evidence reveals that maternal dietary habits play a crucial role in the development of hypertension in adult offspring. In humans, increased fat consumption has been considered responsible for obesity and associated diseases. Maternal diets rich in saturated
You-Lin Tain, Chien-Ning Hsu
openaire   +2 more sources

Starch plus sunflower oil addition to the diet of dry dairy cows results in a trans-11 to trans-10 shift of biohydrogenation [PDF]

open access: yes, 2013
Trans fatty acids (FA), exhibit different biological properties. Among them, cis-9,trans-11 conjugated linoleic acid has some interesting putative health properties, whereas trans-10,cis-12 conjugated linoleic acid has negative effects on cow milk fat ...
Enjalbert, Francis   +3 more
core   +1 more source

The effects of diet and streptozotocin on metabolism and gut microbiota in a type 2 diabetes mellitus mouse model

open access: yesFood and Agricultural Immunology, 2020
Diabetes mellitus is a metabolic disorder disease. Diabetes models can be established using diet and/or chemical agents. However, the effects of these methods on the intestinal microbiota are poorly understood. In this study, C57BL/6 mice were fed with a
Ruiyang Yin   +4 more
doaj   +1 more source

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