Results 91 to 100 of about 834,651 (394)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Effect of Diet Containing Gracilaria Sp. Waste and Multi-Enzyme Additives on Blood Lipid Profile of Local Duck

Animal Production: Indonesian Journal of Animal Production, 2016
This study was aimed to evaluate the effect of diet containing waste of seaweed Gracilaria sp. on local duck blood lipid profiles including cholesterol, triglycerides, low density lipoprotein (LDL), and high density lipoprotein (HDL).
Nurul Frasiska, Edjeng Suprijatna, Siti Susanti   +2 more
doaj   +1 more source

Cholesterol and coronary heart disease: screening and treatment [PDF]

, 1998
Coronary heart disease (CHD) is a major cause of morbidity and mortality in the United Kingdom, accounting for just under one quarter of all deaths in 1995: 27% among men and 21% among women.1 Although many CHD deaths occur among elderly people, CHD ...
Ebrahim, S., Lampe, F., McCabe, C., Payne, N., Pickin, M., Sampson, F., Sheldon, T.A., Smith, G.D., Wannamthee, G., Ward, S.   +9 more
core   +2 more sources

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

Biochemical changes associated with low and very low calorie diets on lipid metabolism, iron profile and kidney function in obese rats

Clinical Nutrition Experimental, 2020
Summary: Obesity is the most prevalent nutritional disorder. Healthy diets helps people maintain and improve their general health. This study aimed to assessment of low and very low calorie diets through determination of its effect on lipid metabolism ...
H.A. Abdel Maksoud, Mohamed G. Elharrif, Raafat R. Mohammed, M.A. Omnia, Nihal E. El Sayed   +4 more
doaj   +1 more source

High-Lipid Diet Intake Is a Possible Predisposing Factor in the Development of Hypogonadal Osteoporosis.

The Japanese Journal of Physiology, 1996
The effects of a high-lipid diet on the intestinal transference of Ca2+ and the activities of intestinal enzymes were studied in ovariectomized rats. The plasma Ca2+ level and urinary loss of Ca2+ were also observed. Ovariectomy decreased both alkaline phosphatase (AP) and calcium ATPase (Ca(2+)-ATPase) activity, and also reduced the mucosal ...
S, Chanda, M N, Islam, P, Pramanik, C, Mitra   +3 more
openaire   +3 more sources

Central functions altered by chronic high-lipids diets enriched with omega 3, omega 6 or saturated fat [PDF]

Proceedings of the Nutrition Society, 2011
High-fat diets consumption induces low-grade obesity-related inflammation (Clark et al, 2011). The blood-brain barrier (BBB) can be damaged by immune cells invasion facilitated by pro-inflammatory cytokines. Interestingly, omega 3 fatty acids inhibit the production of pro-inflammatory cytokines, and omega 3 fatty acids supplementation (DHA) can ...
Val-Laillet, David, Meurice, Paul, Lalles, Jean-Paul, Malbert, Charles-Henri   +3 more
openaire   +3 more sources

High Fat Diet-Induced miR-122 Regulates Lipid Metabolism and Fat Deposition in Genetically Improved Farmed Tilapia (GIFT, Oreochromis niloticus) Liver

Frontiers in Physiology, 2018
The liver is an important organ for the regulation of lipid metabolism. In genetically improved farmed tilapia (GIFT, Oreochromis niloticus), fat deposition in the liver occurs when they are fed high-lipid diets over a long term.
J. Qiang, Yifan Tao, Jingwen Bao, De-Ju Chen, H. Li, Jie He, P. Xu   +6 more
semanticscholar   +1 more source

Serum and synovial fluid lipidomic profiles predict obesity-associated osteoarthritis, synovitis, and wound repair [PDF]

, 2017
High-fat diet-induced obesity is a major risk factor for osteoarthritis (OA) and diminished wound healing. The objective of this study was to determine the associations among serum and synovial fluid lipid levels with OA, synovitis, adipokine levels, and
Guilak, Farshid, Kimmerling, Kelly A, Little, Dianne, Wu, Chia-Lung   +3 more
core   +2 more sources

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source