Results 121 to 130 of about 936,050 (338)

Mechanisms linking colorectal cancer to the consumption of (processed) red meat : a review [PDF]

, 2015
Colorectal cancer (CRC) is the third most commonly diagnosed cancer in the world. The vast majority of CRC cases have been linked to environmental causes rather than to heritable genetic changes.
De Smet, Stefaan, Demeyer, Daniël, Mertens, Birgit, Ulens, Michèle   +3 more
core   +2 more sources

Gut Microbiota‐Derived Anandamide Mediates the Therapeutic Effects of Urolithin A on Alcohol‐Induced Cognitive and Social Dysfunction via CB1R‐DRD2‐RAP1 Signaling Axis

Advanced Science, EarlyView.
This study reveals that Urolithin A (UA) counteracts alcohol‐induced cognitive and social dysfunction (AICSD) via a gut microbiome‐dependent mechanism. UA‐enriched Bacteroids sartorii and Parabacteroids distasonis elevate anandamide (AEA), which activates the CB1R‐DRD2‐Rap1 signaling cascade to drive synaptic repair and reduce neuroinflammation ...
Hongbo Zhang, Zibin Li, Yao Xiao, Ji Bian, Caian He, Chao Liu, Lan Gong, Lin Han, Zhigang Liu, Min Wang   +9 more
wiley   +1 more source

Dietary starch to lipid ratios influence growth performance, nutrient utilisation and carcass traits in broiler chickens offered diets with different energy densities.

PLoS ONE, 2018
Twelve experimental diets with three levels of energy densities (11.25, 12.38 and 13.50 MJ/kg) and fours levels of starch to lipid ratios (14:1, 12:1, 7:1, 4:1) were offered to 288 male Ross 308 broiler chickens.
Ali Khoddami, Peter V Chrystal, Peter H Selle, Sonia Yun Liu   +3 more
doaj   +1 more source

Replacement of dietary saturated fatty acids by trans fatty acids lowers serum HDL cholesterol and impairs endothelial function in healthy men and women [PDF]

, 2001
We tested whether trans fatty acids and saturated fatty acids had different effects on flow-mediated vasodilation (FMD), a risk marker of coronary heart disease (CHD). Consumption of trans fatty acids is related to increased risk of CHD, probably through
Bots, M.L., Katan, M.B., Roos, N.M., de
core   +2 more sources

Remimazolam Ameliorates Autistic‐Like Behaviors via Suppression of Ferroptosis in VTA Dopaminergic Neurons in a Mouse Model of ASD

Advanced Science, EarlyView.
The ultra‐short‐acting sedative remimazolam has a sustained therapeutic effect on the core symptoms of VPA‐exposed mice. Remimazolam, a GABA agonist, exerts its therapeutic effects by protecting dopamine neurons in the VTA of VPA‐exposed mice. Meanwhile, ferroptosis is the critical mechanism by which remimazolam protects VTA dopaminergic neurons and ...
Yuxin Zhang, Jianwei Lin, Chaoyang Tong, Xin Fu, Mengqin Shan, Yue Huang, Kan Zhang, Jijian Zheng   +7 more
wiley   +1 more source

High-glucose diets differentially modulate phosphatidylcholine metabolism and fecundity in Caenorhabditis elegans

Frontiers in Cell and Developmental Biology
BackgroundCaenorhabditis elegans fed a high-glucose Escherichia coli OP50 diet exhibit reduced fecundity, but the underlying mechanisms remain unclear.MethodsA differential high-glucose diet paradigm was established using C.
Chao-Wen Wang, Chao-Wen Wang, Phebe Chiu, Sophia Monsalve, Ricardo Roure, Xiaofei Bai, Jia-Jin Law, Yu-Ching Wu, Yet-Ran Chen, You-Liang Cheng, Rey-Huei Chen, Yi-Chun Wu   +11 more
doaj   +1 more source

Differential expression of lipid metabolism‐related genes and miRNAs in Ctenopharyngodon idella liver in relation to fatty liver induced by high non‐protein energy diets

, 2017
To explore the mechanism of fatty liver formation induced by high non-protein energy diets in grass carp (Ctenopharyngodon idella), basal diet and high-energy diets were fed to juvenile grass carp for 9 weeks.
Junli Wang, Ronghua Lu, Jun-jun Sun, Dizhi Xie, Feng Yang, G. Nie   +5 more
semanticscholar   +1 more source

Development of growth rate, body lipid, moisture, and energy models for white sturgeon (Acipenser transmontanus) fed at various feeding rates. [PDF]

, 2017
The objectives were to develop and evaluate: 1) growth rate models, 2) body lipid, moisture, and energy models for white sturgeon fed at various feeding rates (FR; % body weight [BW] per day) and then evaluate responses at proportions of optimum feeding ...
Fadel, James G, Hung, Silas SO, Lee, Seunghyung, Sonmez, Ozan   +3 more
core   +1 more source

Cancer Cell‐Intrinsic Cholesterol Induces Lipid‐Associated Macrophage Differentiation via SP1 Palmitoylation to Promote Prostate Cancer Progression

Advanced Science, EarlyView.
Cancer cell‐intrinsic cholesterol promotes the S‐palmitoylation of SP1, increasing its nuclear translocation and driving the transcription and secretion of MDK, which in turn facilitates the differentiation of macrophages into a lipid‐associated phenotype.
Shirong Peng, Weilong Lin, Zean Li, Ruilin Zhuang, Shengmeng Peng, Bingheng Li, Bingliang Chen, Yong Luo, Yuan Ou, Wei Zhuang, Tao Du, Kaiwen Li, Hai Huang   +12 more
wiley   +1 more source

Growth, fillet yield, and muscle quality traits are not affected by a genotype by diet interaction in rainbow trout consuming diets that differ in lipid content

Journal of the World Aquaculture Society
In this study, selectively bred rainbow trout (Oncorhynchus mykiss) with improved fillet yield were reared on three commercially available diets that varied in dietary lipid content: low lipid (LL, 18%), moderate lipid (ML, 24%), and high lipid (HL, 29 ...
Beth M. Cleveland, Lisa M. Radler, Tim D. Leeds   +2 more
doaj   +1 more source