Results 41 to 50 of about 711,574 (300)
Handmade alcoholic beverages are produced in clandestine laboratories. There are reports concerning the of counterfeit alcoholic beverages adulterated with psychoactive drugs.
Morvarid Sadat Miri +3 more
doaj +1 more source
Y chromosome haplotypes are particularly useful in deciphering human evolutionary history because they accentuate the effects of drift, migration, and range expansion.
P. Underhill +8 more
semanticscholar +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
Hemoglonbin Typing by High Performance Liquid Chromatography
-
Thanusak Tatu, P Kaidkaseam, P Hathirat
doaj
Objectives Non-adherence to therapy is an important cause of suboptimal blood pressure control but few practical tools exist to accurately and routinely detect it.
M. Tomaszewski +10 more
semanticscholar +1 more source
EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche +8 more
wiley +1 more source
Fractionation of fecal neutral steroids by high performance liquid chromatography.
Fecal neutral steroids were fractionated by high performance liquid chromatography (HPLC) into three major fractions: 5 beta-H, 3-keto steroids; 5 beta-H, 3 beta-hydroxy steroids; and 5 alpha-H and delta 5-3 beta-hydroxy steroids.
E M Jackson +3 more
doaj +1 more source
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima +6 more
wiley +1 more source
Multidimensional High-Performance Liquid Chromatography [PDF]
This chapter explores alternative methods for obtaining chemical fingerprints, that being, multidimensional high-performance liquid chromatography (MDHPLC). HPLC is the most commonly used analytical separation technique for the determination of components in complex mixtures as it offers high sensitivity and can be highly selective.
Milroy, Coleen S. (R13959) +3 more
openaire +2 more sources
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source

