Results 91 to 100 of about 616,436 (300)

High-sensitivity C-reactive protein as a biomarker of cardiovascular events

National Journal of Physiology, Pharmacy and Pharmacology
Background: Development of high sensitivity CRP (Hs-CRP) assays has improved the role of this acute phase reactant in predicting the first cardiovascular events. Hs-CRP levels partially reflect the extent of myocardial necrosis and can be used to predict
Dhwani Bhaveshkumar Pandya, Bharat Bhetariya, Nayan Koitiya   +2 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Birth Weight, Current Anthropometric Markers, and High Sensitivity C-Reactive Protein in Brazilian School Children [PDF]

, 2020
Studies have shown associations of birth weight with increased concentrations of high sensitivity C-reactive protein. This study assessed the relationship between birth weight, anthropometric and metabolic parameters during childhood, and high ...
Camile Boscaini, Lucia Campos Pellanda
core  

Predictive value of high sensitivity C-reactive protein in patients with ST-elevation myocardial infarction treated with percutaneos coronary intervention [PDF]

, 2008
Aims To evaluate the predictive value of high sensitivity (hs) C-reactive protein levels on long-term survival in patients with ST-elevation myocardial infarction (STEMI) treated with primary PCI.
ORTOLANI, PAOLO, BALDAZZI, FEDERICA, TAGLIERI, NEVIO, T. Palmerini, SAIA, FRANCESCO, C. Marrozzini, R. Grilli, BRANZI, ANGELO, MARZOCCHI, ANTONIO, S. Silenzi, BACCHI REGGIANI, MARIA LETIZIA, P. Guastaroba   +11 more
core   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Plasma Aβ42 correlates positively with increased body fat in healthy individuals [PDF]

, 2005
Obesity and overweight, well known risk factors for cardiovascular disease and type 2 diabetes, are now associated with Alzheimer's disease (AD). It remains to be determined if obesity and overweight contribute to the risk of developing AD through ...
Balakrishnana, K., Beilbye, J., Newton, Robert, Nolan, David, Martins, Ralph N., Newton, R., Mehta, P.D., Pankaj D. Mehta, David Nolan, Kelvin Balakrishnan, Galvão, Daniel A., Ralph N. Martins, Beilby, J., Gandy, Samuel E., Samuel E. Gandy, John Beilby, Giuseppe Verdile, Balakrishnan, Kelvin, Martins, R., Gandy, S., Verdile, G., Verdile, Giuseppe, Gandy, S.E., Galvao, D., Galvão, D.A., Nolan, D., Mehta, Pankaj D., Balakrishnan, K., Daniel A. Galvão, Beilby, John, Martins, R.N., Robert Newton, Mehta, P.   +32 more
core   +2 more sources

Within-subject variation of C-reactive protein and high-sensitivity C-reactive protein: A systematic review and meta-analysis.

PLoS ONE
BackgroundC-reactive protein (CRP) and high-sensitivity C-reactive protein (hsCRP) are measures of inflammation used in diagnosis, to guide treatment decisions, and in disease prediction.
Alex Gough, Alice Sitch, Erica Ferris, Tom Marshall   +3 more
doaj   +1 more source

Inverted J-Shaped Association of High-Sensitivity C-Reactive Protein with the Levels of Serum Uric Acid: Cross-Sectional and Longitudinal Analyses

Journal of Inflammation Research, 2022
Xing Zhen Liu,1,* Ya Jun Tian,1,* Jie Fan,2 Lian Yong Liu3 1Department of Health Management, Hangzhou Aeronautical Sanatorium for Special Service of China Air Force, Hangzhou, People’s Republic of China; 2Department of Traffic Management ...
Liu XZ, Tian YJ, Fan J, Liu LY
doaj  

Increased levels of high-sensitivity C-reactive protein in coronary artery diseases

ARYA Atherosclerosis, 2018
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Yousef Rasmi
doaj   +1 more source