Results 61 to 70 of about 616,436 (300)

Evaluating the Quality of Research into a Single Prognostic Biomarker: A Systematic Review and Meta-analysis of 83 Studies of C-Reactive Protein in Stable Coronary Artery Disease [PDF]

, 2010
Background: Systematic evaluations of the quality of research on a single prognostic biomarker are rare. We sought to evaluate the quality of prognostic research evidence for the association of C-reactive protein (CRP) with fatal and nonfatal events ...
Adam D Timmis, Kate S L McAllister, Fitzpatrick Natalie K., J. Damant (7608818), Stephen Palmer, McAllister, Kate, Aroon D Hingorani, A. D. Timmis (7608830), Hingorani, AD, Chen Ruoling, A. D. Hingorani (7602500), Damant Jacqueline, Fitzpatrick, NK, Timmis Adam D., Keith R. Abrams, J. C. Kaski (7608827), Palmer, S, Fitzpatrick, Natalie K., Chen, Ruoling, Abrams, Keith R, Harry Hemingway, Timmis, Adam D, Philipson, P, Santiago Moreno, Natalie K. Fitzpatrick, Palmer, Stephen, Turnbull, Fiona Mary, McAllister, Kate S L, Damant, J, Timmis, Adam D., K. S. L. McAllister (7608824), Moreno, Santiago, Kaski, JC, Philipson Peter, Hingorani, Aroon D, Hemingway Harry, Adam D. Timmis, Fitzpatrick, Natalie K, Abrams Keith R., Keith R. Abrams (7579436), Shipley, Martin, Palmer Stephen, Hemingway, Harry, Shipley Martin, Abrams, Keith R., Chen, R, H. Hemingway (7608809), McAllister, KSL, Shipley, M, Timmis, AD, Moreno Santiago, Natalie K Fitzpatrick, Hingorani Aroon D., Damant, Jacqueline, Juan Carlos Kaski, Fitzpatrick, Natalie, Philipson, Peter, McAllister, KS, N. K. Fitzpatrick (7608815), Kaski Juan Carlos, P. Philipson (7608812), Abrams, Keith, Kate S. L. McAllister, S. Palmer (3693193), Martin Shipley, Peter Philipson, Jacqueline Damant, M. Shipley (7608821), McAllister Kate S. L., Santiago Moreno (90184), Chen, RL, Moreno, S, Mcallister, Katherine, Abrams, KR, R. Chen (576618), Hingorani, Aroon D., Kaski, Juan Carlos, Keith R Abrams, Hemingway, H, Timmis, Adam, Aroon D. Hingorani, Ruoling Chen, Philipson, Pete, Hingorani, Aroon   +83 more
core   +1 more source

High-Sensitivity C-Reactive Protein Leads to Increased Incident Metabolic Syndrome in Women but Not in Men: A Five-Year Follow-Up Study in a Chinese Population

Diabetes, Metabolic Syndrome and Obesity, 2020
Guo-bao Hong,1,2 Pei-chun Gao,1,3 Yun-yin Chen,1 Yue Xia,1 Xiao-su Ke,1 Xiao-fei Shao,1 Chong-xiang Xiong,1 Hai-shan Chen,1 Hua Xiao,1 Jing Ning,1 He-qun Zou1 1Department of Nephrology, Institute of Nephrology and Urology, The Third Affiliated Hospital ...
Hong G, Gao P, Chen Y, Xia Y, Ke X, Shao X, Xiong C, Chen H, Xiao H, Ning J, Zou H   +10 more
doaj  

Clinical significance of high-sensitivity C- reactive protein in systemic sclerosis

Научно-практическая ревматология, 2016
Objective. To determine diagnostic and prognostic significance of high-sensitivity Creactive protein (hsCRP) in systemic sclerosis (SS), to define relationship of this factor with activity of the disease and cardiovascular pathology, to assess role of ...
T. A. Nevskaya, A. A. Novikov, E. N. Alexandrova, E. S. Mach, M. E. Zapryagaeva, A. I. Speransky, N. G. Guseva, L. P. Ananjeva   +7 more
doaj   +1 more source

High-sensitivity C-reactive protein in heart failure with preserved ejection fraction. [PDF]

PLoS ONE, 2018
BACKGROUND:Microvascular inflammation may contribute to the pathogenesis of both heart failure with preserved ejection fraction (HFpEF) and pulmonary hypertension (PH).
Hilary M DuBrock, Omar F AbouEzzeddine, Margaret M Redfield   +2 more
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Inflammation and endothelial function: Direct vascular effects of human C-reactive protein on nitric oxide bioavailability [PDF]

, 2005
Background - Circulating concentrations of the sensitive inflammatory marker C-reactive protein (CRP) predict future cardiovascular events, and CRP is elevated during sepsis and inflammation, when vascular reactivity may be modulated.
Stidwill, RP, Singer, M, MacAllister, RJ, Storry, C, Pepys, MB, Vallance, P, Deanfield, JE, Hineorani, AD, Clapp, BR, Hirschfield, GM, Gallimore, JR   +10 more
core  

Point: High-Sensitivity C-Reactive Protein and Cardiac C-Reactive Protein Assays: Is There a Need to Differentiate? [PDF]

Clinical Chemistry, 2006
Recent evidence has shown that inflammation plays a pivotal role in the inception and progression of atherosclerosis, and population studies have demonstrated a strong and independent association between baseline concentrations of inflammatory biomarkers and future coronary events. Because the majority of individuals who develop coronary events are not
Nader, Rifai, Christie M, Ballantyne, Mary, Cushman, Daniel, Levy, Gary L, Myers   +4 more
openaire   +2 more sources

Functional activities of C-reactive protein on neutrophils [PDF]

C-reactive protein (CRP) is a member of the pentraxin family which opsonises S. pneumoniae through its binding to phosphorylcholine. In addition, CRP binds to Fcγ receptors: FcγRI with high affinity and, probably, FcγRIIA with lower affinity.
Rodriguez, Jairo Antonio
core   +1 more source

High-sensitivity C-reactive protein and exercise-induced changes in subjects suspected of coronary artery disease

Journal of Inflammation Research, 2014
Mette Rauhe Mouridsen,1 Olav Wendelboe Nielsen,1 Christian Malchau Carlsen,1 Nick Mattsson,1 Martin H Ruwald,2 Zeynep Binici,3 Ahmad Sajadieh1 1Department of Cardiology, Copenhagen University Hospital of Bispebjerg, Copenhagen NV, Denmark; 2Department of
Mouridsen MR, Nielsen OW, Carlsen CM, Mattsson N, Ruwald MH, Binici Z, Sajadieh A   +6 more
doaj