Results 71 to 80 of about 709,711 (305)

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

Birth Weight, Current Anthropometric Markers, and High Sensitivity C-Reactive Protein in Brazilian School Children

Journal of Obesity, 2015
Studies have shown associations of birth weight with increased concentrations of high sensitivity C-reactive protein. This study assessed the relationship between birth weight, anthropometric and metabolic parameters during childhood, and high ...
Camile Boscaini, Lucia Campos Pellanda
doaj   +1 more source

Association of serum uric acid with high-sensitivity C-reactive protein in postmenopausal women. [PDF]

, 2016
OBJECTIVES: To explore the independent correlation between serum uric acid and low-grade inflammation (measured by high-sensitivity C-reactive protein, hs-CRP) in postmenopausal women.
Darabi, H, Moshtaghi, D, Nabipour, Iraj, Ostovar, Afshin, Raeisi, Alireza, Rezaei, P, Vahdat, Katayoun   +6 more
core   +1 more source

Specific detection of dengue and Zika virus antibodies using envelope proteins with mutations in the conserved fusion loop [PDF]

, 2017
Detection of antibodies is widely used for the diagnosis of infections with arthropod-borne flaviviruses including dengue (DENV) and Zika virus (ZIKV). Due to the emergence of ZIKV in areas endemic for DENV, massive co-circulation is observed and methods
Barzon, Luisa, Brites, Carlos, Drexler, Jan Felix, Ferreira, Orlando C, Kumbukgolla, Widuranga, Moges, Beyene, Moreira-Soto, Andres, Pal\uf9, Giorgio, Rockstroh, Alexandra, Sarno, Manoel, Schmidt-Chanasit, Jonas, Sinigaglia, Alessandro, Ulbert, Sebastian   +12 more
core   +2 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

The association study of high-sensitivity C-reactive protein, pentraxin 3, nitrotyrosine, and insulin dose in patients with insulin-treated type 2 diabetes mellitus

Therapeutics and Clinical Risk Management, 2018
Cornelia Bala, Adriana Rusu, Dana Mihaela Ciobanu, Anca Elena Craciun, Gabriela Roman Department of Diabetes and Nutrition, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania Purpose: The objective of this study was to examine the ...
Bala C, Rusu A, Ciobanu DM, Craciun AE, Roman G   +4 more
doaj  

Association of Three Novel Inflammatory Markers: Lymphocyte to HDL‐C Ratio, High‐Sensitivity C‐Reactive Protein to HDL‐C Ratio and High‐Sensitivity C‐Reactive Protein to Lymphocyte Ratio With Metabolic Syndrome

Endocrinology, Diabetes & Metabolism
Objective We aimed to compare the association of three novel inflammatory indicators with metabolic syndrome (MetS) among Mashhad stroke and heart atherosclerotic disorder (MASHAD) cohort participants.
Rana Kolahi Ahari, Nazanin Akbari, Negin Babaeepoor, Zahra Fallahi, Sara Saffar Soflaei, Gordon Ferns, Mahmoud Ebrahimi, Mohsen Moohebati, Habibollah Esmaily, Majid Ghayour‐Mobarhan   +9 more
doaj   +1 more source

Inverted J-Shaped Association of High-Sensitivity C-Reactive Protein with the Levels of Serum Uric Acid: Cross-Sectional and Longitudinal Analyses

Journal of Inflammation Research, 2022
Xing Zhen Liu,1,* Ya Jun Tian,1,* Jie Fan,2 Lian Yong Liu3 1Department of Health Management, Hangzhou Aeronautical Sanatorium for Special Service of China Air Force, Hangzhou, People’s Republic of China; 2Department of Traffic Management ...
Liu XZ, Tian YJ, Fan J, Liu LY
doaj  

Recombinant Envelope-Proteins with Mutations in the Conserved Fusion Loop Allow Specific Serological Diagnosis of Dengue-Infections [PDF]

, 2015
Dengue virus (DENV) is a mosquito-borne flavivirus and a major international public health concern in many tropical and sub-tropical areas worldwide. DENV is divided into four major serotypes, and infection with one serotype leads to immunity against the
Barzon, Luisa, Niedrig, Matthias, Pacenti, Monia, Palu', Giorgio, Rockstroh, Alexandra, Ulbert, Sebastian   +5 more
core   +4 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source