Results 61 to 70 of about 25,285 (264)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Wheel Wear Predictions and Analyses of High-Speed Trains
Nonlinear Engineering, 2012 Wear of wheel profiles is one of the most critical issues affecting cost and performance of railway transportation systems. By altering the profile from the shape originally chosen by the designer, wear has a very large effect on vehicle dynamics, so ...
Jin X. C., Ahmadian
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Overviewing Braking Technology of the High-speed Trains
机车电传动, 2011 The relationship between the braking system and the security of the high-speed trains was expounded, comparative analysis about the brake modes and the corresponding braking performance as well as reviews of their domestic and oversea applications was ...
张建柏, 彭辉水, 倪大成, 刘雄
doaj
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
aircraft and high-speed train substitution
, 2010 This book section is from A Dictionary of Transport Analysis: This concise and clearly focused Dictionary, with contributions by the leading authorities in their fields, brings order and clarity to a topic that can suffer from confusion over terminology and concepts.
openaire +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Research on Aerodynamic Noise Reduction for High-Speed Trains
Shock and Vibration, 2016 A broadband noise source model based on Lighthill’s acoustic theory was used to perform numerical simulations of the aerodynamic noise sources for a high-speed train.
Yadong Zhang +4 more
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Journal of Advanced Transportation, 2019 The cruise control of high-speed trains is challenging due to the presence of time-varying air resistance coefficients and control constrains. Because the resistance coefficients for high-speed trains are not accurately known and will change with the ...
Xiaokang Xu +7 more
doaj +1 more source