Results 11 to 20 of about 11,387,151 (316)
High-Throughput Glycomic Methods
Chemical Reviews, 2022 Glycomics aims to identify the structure and function of the glycome, the complete set of oligosaccharides (glycans), produced in a given cell or organism, as well as to identify genes and other factors that govern glycosylation. This challenging endeavor requires highly robust, sensitive, and potentially automatable analytical technologies for the ...
Irena Trbojević-Akmačić +6 more
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Connectomics in high throughput [PDF]
Nature Methods, 2020 BRICseq provides access to brain-wide connectivity and can be combined with functional and transcriptomic studies for a comprehensive view of neuronal circuitry.
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High‐Throughput SNP Genotyping [PDF]
ChemInform, 2002 AbstractWhole genome approaches using single nucleotide polymorphism (SNP) markers have the potential to transform complex disease genetics and expedite pharmacogenetics research. This has led to a requirement for high‐throughput SNP genotyping platforms. Development of a successful high‐throughput genotyping platform depends on coupling reliable assay
Jenkins, Suzanne, Gibson, Neil
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SLAS Discovery, 2022 Rapid triage of compounds acting via undesired mechanisms is a crucial stage in a high-throughput screening (HTS) cascade to ensure time and resource is efficiently assigned to the most propitious hits.
Rachel Moore +4 more
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High-throughput tetrad analysis [PDF]
Nature Methods, 2013 Tetrad analysis has been a gold-standard genetic technique for several decades. Unfortunately, the need to manually isolate, disrupt and space tetrads has relegated its application to small-scale studies and limited its integration with high-throughput DNA sequencing technologies.
Ludlow, Catherine L. +9 more
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Energy Science & Engineering, 2023 Polymer components, in particular, backsheets (BSs) and ethylene‐vinyl acetate (EVA) encapsulants, play a crucial role in the degradation of commercial silicon photovoltaic (PV) modules.
Claudia Buerhop +4 more
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High-throughput Technology and High-throughput Factory
Nihon Kessho Gakkaishi, 2003 Structural Genomics has launched over the world including National Project of Protein Structural and Functional Analysis in Japan in a post-genomic era. It remains many bottlenecks to determine the protein structures with SR protein crystallography based on full-genome sequence information in high throughput manner.
MIYANO, Masashi +2 more
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Advances in Non-Coding RNA Sequencing
Non-Coding RNA, 2021 Non-coding RNAs (ncRNAs) comprise a set of abundant and functionally diverse RNA molecules. Since the discovery of the first ncRNA in the 1960s, ncRNAs have been shown to be involved in nearly all steps of the central dogma of molecular biology.
Julia Micheel +2 more
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Association between LRP1 C766T polymorphism and Alzheimer’s disease susceptibility: a meta-analysis
Scientific Reports, 2017 Low density lipoprotein receptor-related protein 1 (LRP1) C766T polymorphism (rs1799986) has been extensively investigated for Alzheimer’s disease (AD) susceptibility. However, results in different studies have been contradictory. Therefore, we conducted
Yun Wang +9 more
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Integrative prediction of gene expression with chromatin accessibility and conformation data
Epigenetics & Chromatin, 2020 Background Enhancers play a fundamental role in orchestrating cell state and development. Although several methods have been developed to identify enhancers, linking them to their target genes is still an open problem. Several theories have been proposed
Florian Schmidt +2 more
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