Results 21 to 30 of about 604,403 (268)

The Role of Non-Coding RNAs in the Human Placenta

open access: yesCells, 2022
Non-coding RNAs (ncRNAs) play a central and regulatory role in almost all cells, organs, and species, which has been broadly recognized since the human ENCODE project and several other genome projects.
Milena Žarković   +3 more
doaj   +1 more source

Corrosion of iron and nickel based alloys in sulphuric acid: Challenges and prevention strategies

open access: yesJournal of Materials Research and Technology, 2023
Sulphuric acid (H2SO4) is widely used in various industrial processes, including fertilizer production. However, its highly corrosive nature poses a significant challenge to the materials used for transport and storage, particularly metals and alloys ...
Ayoub Ouarga   +5 more
doaj   +1 more source

Interplay between transforming growth factor-β and Nur77 in dual regulations of inhibitor of differentiation 1 for colonic tumorigenesis

open access: yesNature Communications, 2021
Inhibitor of Differentiation 1 (ID1) is an oncogene for colorectal cancer. Here, the authors show a complex interplay between nuclear receptor Nur77 and Transforming Growth Factor-β (TGFβ) to regulate ID1 expression at both transcriptional and post ...
Boning Niu   +9 more
doaj   +1 more source

High-Throughput Phenomics

open access: yes, 2015
Standard protocols are available in order to apply Phenotype MicroArray (PM) technology to characterize different groups of microorganisms. Nevertheless, there is the need to pay attention to several crucial steps in order to obtain high-quality and reproducible data from PM, such as the choice of the Dye mix, the type and concentration of the carbon ...
Carlo, Viti   +4 more
openaire   +3 more sources

High-throughput programmable cryptocoprocessor [PDF]

open access: yesIEEE Micro, 2004
High-speed Internet protocol security (IPsec) applications require high throughput and flexible security engines. A loosely coupled cryptocoprocessor based on the advanced encryption standard combines high throughput with programmability. using domain-specific instructions and design principles such as control hierarchy and block pipelining, the ...
Alireza Hodjat, Ingrid Verbauwhede
openaire   +1 more source

Cost Estimation Tool for Metallic Parts Made by Casting: A Case Study

open access: yesMetals, 2023
This work presents a mathematical tool to estimate the cost of fabricating pumps by traditional casting. The drivers that most affect the cost of the process are identified in each step of the procedure, i.e., material, labour, energy, tools and general ...
Itziar Iraola-Arregui   +2 more
doaj   +1 more source

A high-throughput human tissue model for respiratory viruses: Automating the use of human airway epithelial tissues for faster drug discovery

open access: yesSLAS Discovery
Animal testing for drug discovery is expensive and the decision to test a compound in an in vivo model should be carefully considered. In addition, the FDA Modernization Act has resulted in the allowance of alternatives to animal models for testing the ...
N. Miranda Nebane   +7 more
doaj   +1 more source

Genomic analysis of 61 Chlamydia psittaci strains reveals extensive divergence associated with host preference

open access: yesBMC Genomics, 2023
Background Chlamydia (C.) psittaci, the causative agent of avian chlamydiosis and human psittacosis, is a genetically heterogeneous species. Its broad host range includes parrots and many other birds, but occasionally also humans (via zoonotic ...
Konrad Sachse   +7 more
doaj   +1 more source

High-throughput detection of metal contamination in HTS outputs

open access: yesSLAS Discovery, 2022
Large compound libraries utilised for HTS often include metal contaminated compounds which can interfere with assay signal or target biology, and therefore appear as hits.
Corinne Molyneux   +5 more
doaj   +1 more source

Dynamic Proteomic Analysis of Pancreatic Mesenchyme Reveals Novel Factors That Enhance Human Embryonic Stem Cell to Pancreatic Cell Differentiation

open access: yesStem Cells International, 2016
Current approaches in human embryonic stem cell (hESC) to pancreatic beta cell differentiation have largely been based on knowledge gained from developmental studies of the epithelial pancreas, while the potential roles of other supporting tissue ...
Holger A. Russ   +8 more
doaj   +1 more source

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