Results 41 to 50 of about 11,387,151 (316)
The new era of high throughput nanoelectrochemistry
, 2022 Scanning electrochemical probe microscopies (SEPMs) have played a key role in advancing small-scale electrochemistry. SEPMs use an electrochemical probe (micro/nanoelectrode or pipet) to quantify and map local interfacial fluxes of electroactive species ...
Frédéric, Kanoufi +8 more
core +1 more source
Protein synthesis rate is the predominant regulator of protein expression during differentiation
Molecular Systems Biology, 2013 External perturbations, by forcing cells to adapt to a new environment, often elicit large‐scale changes in gene expression resulting in an altered proteome that improves the cell's fitness in the new conditions.
Anders R Kristensen +2 more
doaj +1 more source
Novel Antiretroviral Structures from Marine Organisms
Molecules, 2019 In spite of significant advancements and success in antiretroviral therapies directed against HIV infection, there is no cure for HIV, which scan persist in a human body in its latent form and become reactivated under favorable conditions.
Karlo Wittine +3 more
doaj +1 more source
, 2021 Catalyst screening in olefin polymerization is an inherently complex problem. Even using high-throughput experimentation (HTE) tools, databases are usually tiny (at least when compared to those in pharma), rarely comprised of more than several dozen ...
Roberta Cipullo +10 more
core
New compound sets identified from high throughput phenotypic screening against three kinetoplastid parasites:an open resource [PDF]
, 2015 Using whole-cell phenotypic assays, the GlaxoSmithKline high-throughput screening (HTS) diversity set of 1.8 million compounds was screened against the three kinetoplastids most relevant to human disease, i.e.
Barroso, Vanessa +26 more
core +1 more source
Stem Cells International, 2016 Current approaches in human embryonic stem cell (hESC) to pancreatic beta cell differentiation have largely been based on knowledge gained from developmental studies of the epithelial pancreas, while the potential roles of other supporting tissue ...
Holger A. Russ +8 more
doaj +1 more source
High-Throughput Sequencing Technologies [PDF]
Molecular Cell, 2015 The human genome sequence has profoundly altered our understanding of biology, human diversity, and disease. The path from the first draft sequence to our nascent era of personal genomes and genomic medicine has been made possible only because of the extraordinary advancements in DNA sequencing technologies over the past 10 years.
Reuter, Jason A. +2 more
openaire +2 more sources
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Polyphenol-Based Design of Functional Olive Leaf Infusions
Food Technology and Biotechnology, 2019 The beneficial properties of polyphenols are widely recognized, and polyphenol-rich olive oil, which is part of the typical Mediterranean diet, has been identified as having positive health effects.
Željka Peršurić +3 more
doaj +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source