Results 61 to 70 of about 11,387,151 (316)
High throughput powder diffraction: II Applications of clustering methods and multivariate data analysis [PDF]
, 2004 In high throughput crystallography is possible to accumulate over 1000 powder diffraction patterns on a series of related compounds, often polymorphs. We present a method that can analyse such data, automatically sort the patterns into related clusters ...
Dong, W +5 more
core +1 more source
Extracellular matrix stiffness mediates radiosensitivity in a 3D nasopharyngeal carcinoma model
Cancer Cell International, 2022 Purpose Radiotherapy is one of the essential treatment modalities for nasopharyngeal carcinoma (NPC), however, radioresistance still poses challenges.
Yanhua Fang +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Cell Discovery, 2023 How cells adapt their gene expression to nutritional changes remains poorly understood. Histone H3T11 is phosphorylated by pyruvate kinase to repress gene transcription.
Xinyu Zhang +7 more
doaj +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Novel technologies enable high throughput acquisition of viral phenotypes
, 2022 Fuhrmann, Jeffry J.Viruses of bacteria (bacteriophages) are the most abundant biological entities on the planet. Phages shape their ecosystems by regulating host abundance and driving nutrient cycling.
Haramoto, Kona
core +1 more source
Meta-analysis of kindling-induced gene expression changes in the rat hippocampus
Frontiers in Neuroscience, 2009 Numerous studies have been performed to examine gene expression patterns in the rodent hippocampus in the kindling model of epilepsy. However, recent reviews of this literature have revealed limited agreement among studies.
Sanja Rogic, Paul Pavlidis
doaj +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Ultra-high throughput string matching for deep packet inspection [PDF]
, 2010 Deep Packet Inspection (DPI) involves searching a packet's header and payload against thousands of rules to detect possible attacks. The increase in Internet usage and growing number of attacks which must be searched for has meant hardware acceleration ...
Wang, Xiaojun +7 more
core +1 more source
Pathogens, 2020 To identify genome-based features characteristic of the avian and human pathogen Chlamydia (C.) psittaci and related chlamydiae, we analyzed whole-genome sequences of 33 strains belonging to 12 species. Using a novel genome analysis tool termed Roary ILP
Martin Hölzer +9 more
doaj +1 more source