Results 91 to 100 of about 271,712 (303)
Nature Communications, 2019 Compared to single nucleotide variants and short indels, structural variants (SVs) are often more challenging to detect using high-throughput sequencing based methods. Here, the authors develop LinkedSV, a computational tool for SV detection using linked-
Li Fang +9 more
doaj +1 more source
Journal of Oral Microbiology, 2016 Background: Reports on the composition of oral bacteriome in Arabs are lacking. In addition, the majority of previous studies on other ethnic groups have been limited by low-resolution taxonomic assignment of next-generation sequencing reads. Furthermore,
Nezar Noor Al-hebshi +4 more
doaj +1 more source
The use of coded PCR primers enables high-throughput sequencing of multiple homolog amplification products by 454 parallel sequencing. [PDF]
PLoS ONE, 2007 The invention of the Genome Sequence 20 DNA Sequencing System (454 parallel sequencing platform) has enabled the rapid and high-volume production of sequence data.
Jonas Binladen +6 more
doaj +1 more source
Wheat rusts never sleep but neither do sequencers: will pathogenomics transform the way plant diseases are managed? [PDF]
, 2015 Field pathogenomics adds highly informative data to surveillance surveys by enabling rapid evaluation of pathogen variability, population structure and host ...
Derevnina, Lida, Michelmore, Richard W
core +2 more sources
Kelvin Probe Force Microscopy in Bionanotechnology: Current Advances and Future Perspectives
Advanced Materials, EarlyView.Kelvin probe force microscopy (KPFM) enables the nanoscale mapping of electrostatic surface potentials. While widely applied in materials science, its use in biological systems remains emerging. This review presents recent advances in KPFM applied to biological samples and provides a critical perspective on current limitations and future directions for
Ehsan Rahimi +4 more
wiley +1 more source
DNAscent v2: detecting replication forks in nanopore sequencing data with deep learning
BMC Genomics, 2021 Background Measuring DNA replication dynamics with high throughput and single-molecule resolution is critical for understanding both the basic biology behind how cells replicate their DNA and how DNA replication can be used as a therapeutic target for ...
Michael A. Boemo
doaj +1 more source
Distinguishing low frequency mutations from RT-PCR and sequence errors in viral deep sequencing data [PDF]
, 2015 There is a high prevalence of coronary artery disease (CAD) in patients with left bundle branch block (LBBB); however there are many other causes for this electrocardiographic abnormality.
Haydon, Daniel T. +6 more
core +2 more sources
Advances in MoS2‐Au Nanostructured Platforms for Cancer‐Derived miRNA Detection
Advanced Materials Interfaces, EarlyView.This figure presents the roadmap and scope of this review on microRNA detection technologies, with emphasis on MoS2 and MoS2–Au hybrid nanostructures. It traces the evolution from conventional assays to MoS2‐based SERS platforms, highlights synthesis, interfacial chemistry, and signal‐enhancement mechanisms, and summarizes key challenges and future ...
Faith Mokobi Zablon +2 more
wiley +1 more source
The Plant Genome, 2011 Melon (Cucumis melo L.) ranks among the highest-valued fruit crops worldwide. Some genomic tools are available for this crop, including a Sanger transcriptome. We report the generation of 689,054 C. melo high-quality expressed sequence tags (ESTs) from two 454 sequencing runs, using normalized and nonnormalized complementary DNA (cDNA) libraries ...
Blanca, José Miguel +7 more
openaire +5 more sources
YAMAT-seq: an efficient method for high-throughput sequencing of mature transfer RNAs. [PDF]
, 2017 Besides translation, transfer RNAs (tRNAs) play many non-canonical roles in various biological pathways and exhibit highly variable expression profiles.
Honda, Shozo +5 more
core +2 more sources