Results 211 to 220 of about 149,249 (267)

IBDV-SSA, a novel molecular approach for the recovery of infectious bursal disease virus whole genomes from FTA cards. [PDF]

Microbiol Spectr
Nour I, Álvarez-Narváez S, Kulkarni A, Mohanty SK.   +3 more
europepmc   +1 more source

Leveraging illumina iSeq100 for whole genome sequencing of Salmonella Typhi for a resource-limited setting. [PDF]

Sci Rep
Katuwal N, Naga SR, Shrestha A, Shahi SB, Tamrakar D, Shrestha R.   +5 more
europepmc   +1 more source

Mechanisms of enhancer‐driven oncogene activation

International Journal of Cancer, EarlyView.
Abstract An aggressive subtype of acute myeloid leukemia (AML) is caused by enhancer hijacking resulting in MECOM overexpression. Several chromosomal rearrangements can lead to this: the most common (inv(3)/t(3;3)) results in a hijacked GATA2 enhancer, and there are several atypical MECOM rearrangements involving enhancers from other hematopoietic ...
Joyce Vriend, Ruud Delwel, Dorien Pastoors   +2 more
wiley   +1 more source

Biomarker research for Henoch-Schönlein purpura nephritis based on "omics" techniques. [PDF]

Front Med (Lausanne)
Zhou X, Yuan Z, Jiang H, Ju Y, Chen C, Zhang W, Liu H, Zhang L, Qi M, An D.   +9 more
europepmc   +1 more source

Integrated scFv identification and CAR T cell generation for AML targeting in vivo

International Journal of Cancer, EarlyView.
What's New? Acute myeloid leukemia (AML) is a rapidly progressing blood cancer. Advancing chimeric antigen receptor (CAR) T cell therapies, particularly through rapid translation of single chain variable fragment (scFv) discovery into CAR constructs, may improve clinical outcomes, especially the development of patient individualized CAR T cells.
Yi Liu, Annika Lauk, David Sedloev, Josephine Brysting, Ela Cetin, Chunan Liu, Maximilian Mönnig, Thomas Luft, Haiyang Yun, Michael Schmitt, Tim Sauer, Fengbiao Zhou, Christian Rohde, Carsten Müller‐Tidow   +13 more
wiley   +1 more source

SKiM: accurately classifying metagenomic ONT reads in limited memory. [PDF]

Bioinformatics
Schneggenburger T, Zola J.
europepmc   +1 more source

New cell lines expanding the diversity of Ewing sarcoma models

International Journal of Cancer, EarlyView.
What's New? A chromosomal translocation between the EWSR1 and ETS genes is the key oncogenic driver in Ewing sarcoma. EWSR1::FLI1, the most frequent fusion, is subdivided into different fusion types with unclear prognostic relevance. Here, the authors describe the establishment and characterization of four new, intrinsically immortal, patient‐derived ...
Maximilian Kerkhoff, Christiane Schaefer, Wilhelm G. Dirks, Dawid Krzeciesa, Maximilian Bretschneider, Pauline R. Plaumann, Wiebke K. Guder, Arne Streitbürger, Sonja Herter, Heike Peterziel, Ina Oehme, Felina Zahnow, Thomas G. P. Grünewald, Uta Dirksen   +13 more
wiley   +1 more source

Annotation of gene loci and analysis of expression diversity in sheep immunoglobulin. [PDF]

Front Immunol
Wu M, Chen F, Tang X, Li J, Zhao H, Zhang Y.   +5 more
europepmc   +1 more source

HiFi based metagenomic assembly strategy provides accuracy near isolated genome resolution in MAG assembly

iMetaOmics, EarlyView.
Recovering high‐contiguity, circular bacterial genomes from complex microbiomes (e.g., gut) is challenged by limitations of short‐read and error‐prone long‐read sequencing. This study comprehensively compares PacBio High‐Fidelity (HiFi) sequencing‐based metagenome‐assembled genomes (MAGs) against Illumina MAGs, Oxford Nanopore Technologies (ONT) MAGs ...
Feilong Deng, Yanhua Han, Minghui Li, Yunjuan Peng, Jianmin Chai, Guan Yang, Ying Li, Jiangchao Zhao   +7 more
wiley   +1 more source

Draft genome sequences of two strains of <i>Pseudomonas fluorescens sensu stricto</i> isolated from strawberry in Japan. [PDF]

Microbiol Resour Announc
Morohoshi T, Someya N.
europepmc   +1 more source