Results 221 to 230 of about 229,759 (254)

Development of a Multiplexed qPCR Kit for the Detection of Bloodstream Infection

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
The paper presents a novel multiplexed PCR kit designed for the rapid and accurate detection of pathogens causing bloodstream infection (BSI) through the microbial cell‐free DNA (cfDNA) of plasma. This innovative diagnostic tool, capable of identifying pathogens within approximately 1.5 h, shows a high degree of accuracy (90.48% consistency with ...
Kai Niu   +12 more
wiley   +1 more source

Mapping protein–protein interactions by mass spectrometry

open access: yesMass Spectrometry Reviews, EarlyView.
Abstract Protein–protein interactions (PPIs) are essential for numerous biological activities, including signal transduction, transcription control, and metabolism. They play a pivotal role in the organization and function of the proteome, and their perturbation is associated with various diseases, such as cancer, neurodegeneration, and infectious ...
Xiaonan Liu   +4 more
wiley   +1 more source

Exploring the dynamic landscape of immunopeptidomics: Unravelling posttranslational modifications and navigating bioinformatics terrain

open access: yesMass Spectrometry Reviews, EarlyView.
Abstract Immunopeptidomics is becoming an increasingly important field of study. The capability to identify immunopeptides with pivotal roles in the human immune system is essential to shift the current curative medicine towards personalized medicine. Throughout the years, the field has matured, giving insight into the current pitfalls. Nowadays, it is
Daniel Flender   +5 more
wiley   +1 more source

Mass Spectrometry Structural Proteomics Enabled by Limited Proteolysis and Cross‐Linking

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT The exploration of protein structure and function stands at the forefront of life science and represents an ever‐expanding focus in the development of proteomics. As mass spectrometry (MS) offers readout of protein conformational changes at both the protein and peptide levels, MS‐based structural proteomics is making significant strides in the
Haiyan Lu   +4 more
wiley   +1 more source

A cost-effective, high-throughput, highly accurate genotyping method for outbred populations. [PDF]

open access: yesG3 (Bethesda)
Chen D   +12 more
europepmc   +1 more source

Bio-nanopore technology for biomolecules detection. [PDF]

open access: yesAdv Biotechnol (Singap)
Li P   +9 more
europepmc   +1 more source

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