Results 221 to 230 of about 153,654 (268)

CRISPR Enabled Precision Oncology: From Gene Editing to Tumor Microenvironment Remodeling

Med Research, EarlyView.
CRISPR technology has progressed from a prokaryotic immune system to a diverse suite of editing platforms, including Cas nucleases, base and prime editors, and RNA‐targeting enzymes. These advances enable precise genomic and epigenomic interventions, high‐throughput functional screening, and immune engineering.
Kailai Li, Peixin Huang, Yue Qian, Anqi Lin, Jingjun He, Junyi Shen, Li Chen, Kai Miao, Jian Zhang   +8 more
wiley   +1 more source

High-throughput virome profiling reveals complex viral diversity, co-infection patterns, and novel viruses in <i>Cnidium officinale</i> in Korea. [PDF]

Front Plant Sci
Kang JH, Lal A, Kwon M, Kwak M, Jung CR, Kil EJ.   +5 more
europepmc   +1 more source

Integrating Long‐Read Nanopore Sequencing for Precision Resolution of Genomic Variants in Dystonia

Movement Disorders, EarlyView.
Abstract Background Although many individuals with dystonia present with features indicative of single‐gene etiologies, obtaining definitive genetic diagnoses can be challenging. Objective We assessed the value of nanopore‐based long‐read sequencing (LRS) in achieving molecular clarification of dystonic syndromes.
Ugo Sorrentino, Martin Pavlov, Nazanin Mirza‐Schreiber, Melanie Brugger, Theresa Brunet, Eugenia Tsoma, Alice Saparov, Ivana Dzinovic, Philip Harrer, Antonia M. Stehr, Matias Wagner, Erik Tilch, Barbara Wallacher, Shiraz Alhasan, Anne Koy, Alessio Di Fonzo, Miriam Kolnikova, Katarina Kusikova, Petra Havrankova, Raushana Tautanova, Sandy Lösecke, Sebastian Eck, Sylvia Boesch, Jan Necpal, Matej Skorvanek, Robert Jech, Holger Prokisch, Juliane Winkelmann, Konrad Oexle, Elisabeth Graf, Michael Zech   +30 more
wiley   +1 more source

Characteristics and Phylogenetic Analysis of the Complete Chloroplast Genome of <i>Abelmoschus esculentus</i>. [PDF]

Int J Mol Sci
Dong J, Du G, Ji Q, An X, Zhu Z, Tang S, Luo X, Chen C, Liu T, Zou L, Li S, Chen J, An X.   +12 more
europepmc   +1 more source

Decoding the lncRNA World: Comprehensive Approaches to lncRNA Structure and Interactome Studies. [PDF]

Cells
Oh M, Lee BL, Somarowthu S.
europepmc   +1 more source

Poly(A) tail regulation in stem cells and early development. [PDF]

Cell Regen
Miao X, Hu G.
europepmc   +1 more source

Optimized high-throughput whole-genome sequencing workflow for surveillance of influenza A virus. [PDF]

Genome Med
Licheri M, Mwanga M, Licheri MF, Graaf-Rau A, Sägesser C, Bittel P, Harder T, Suter-Riniker F, Kelly JN, Dijkman R.   +9 more
europepmc   +1 more source

<i>TP53</i> Mutations in Mantle Cell Lymphoma: From Backup to Game Changer. [PDF]

J Clin Med
Carazzolo ME, Moioli A, Visco C.
europepmc   +1 more source