Results 91 to 100 of about 61,294 (275)

Erratum: Author Correction: Identification of genes required for eye development by high-throughput screening of mouse knockouts. [PDF]

, 2019
[This corrects the article DOI: 10.1038/s42003-018-0226-0.]
Adissu, Hibret, Asomugha, Chinwe, Beaudet, Arthur L, Berberovic, Zorana, Bohat, Ritu, Bower, Lynette, Braun, Robert E, Brown, Steve DM, Cater, Heather, Clary, David, Clementson-Mobbs, Sharon, Cooper, Ann, de Angelis, Martin Hrabe, Dickinson, Mary E, Edwards, Sydney G, Eskandarian, Mohammed, Flenniken, Ann M, Fletcher, Colin, Flicek, Paul, Gallegos, Juan J, Gao, Xiang, Griffey, Stephen M, Heaney, Jason D, Herault, Yann, Hsu, Chih-Wei, Imai, Denise M, International Mouse Phenotyping Consortium, Joynson, Russell, Justice, Monica J, Kalaga, Sowmya, Karp, Natasha, Kent Lloyd, KC, Krebs, Mark P, Kumar, Vivek, Leonard, Brian C, Mallon, Ann-Marie, Mason, Jeremy, McKerlie, Colin, Meehan, Terrence F, Meziane, Hamid, Moore, Bret A, Moore, Mark, Moshiri, Ala, Murphy, Christopher J, Murray, Stephen A, Newbigging, Susan, Nishina, Patsy M, Nutter, Lauryl MJ, Owen, Celeste, Parkinson, Helen, Philip, Vivek, Ramirez-Solis, Ramiro, Reilly, Christopher, Roux, Michel J, Santos, Luis, Seavitt, John R, Sebbag, Lionel, Seong, JK, Smedley, Damian, Stewart, Michelle, Straiton, Ewan, Suzuki, Tomohiro, Svenson, Karen L, Thomasy, Sara M, Tocchini-Valentini, Glauco, Udensi, Uchechukwu, Wakana, Shigeharu, Wells, Sara, White, Jacqueline K, Wurst, Wolfgang   +69 more
core  

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu, Yinjiao Fei, Jiaxuan Ding, Kexin Shi, Jinyan Luo, Yuchen Zhu, Xingjian Sun, Gefei Jiang, Yuandong Cao, Weilin Xu, Shu Zhou   +10 more
wiley   +1 more source

Clinical Conditions Associated With a High Antinuclear Antibody Titer in Individuals Without Autoimmune Disease

Arthritis Care &Research, EarlyView.
Objective Antinuclear antibodies (ANAs) are present at high titers in 2% of the general population, but their clinical significance in individuals without an autoimmune (AI) disease is not known. We tested the hypothesis that the presence of a high ANA titer in non‐AI conditions is associated with disease.
Matthew Chung, John P. Shelley, Gul Karakoc, John Still, Xiaodi Ruan, Jonathan Mosley, C. Michael Stein, Vivian K. Kawai   +7 more
wiley   +1 more source

3D (Bio) Printing Combined Fiber Fabrication Methods for Tissue Engineering Applications: Possibilities and Limitations

Advanced Functional Materials, EarlyView.
Biofabrication aims at providing innovative technologies and tools for the fabrication of tissue‐like constructs for tissue engineering and regenerative medicine applications. By integrating multiple biofabrication technologies, such as 3D (bio) printing with fiber fabrication methods, it would be more realistic to reconstruct native tissue's ...
Waseem Kitana, Indra Apsite, Leonid Ionov   +2 more
wiley   +1 more source

High‐throughput CRISPRi phenotyping identifies new essential genes in Streptococcus pneumoniae

Molecular Systems Biology, 2017
Genome‐wide screens have discovered a large set of essential genes in the opportunistic human pathogen Streptococcus pneumoniae. However, the functions of many essential genes are still unknown, hampering vaccine development and drug discovery.
Xue Liu, Clement Gallay, Morten Kjos, Arnau Domenech, Jelle Slager, Sebastiaan P van Kessel, Kèvin Knoops, Robin A Sorg, Jing‐Ren Zhang, Jan‐Willem Veening   +9 more
doaj   +1 more source

High throughput phenotyping method for water use efficiency in rice under field conditions : [Abstract, P 6.04] [PDF]

, 2009
A collaborative CIAT/Cirad project aims to create new improved upland rice germplasm for drought tolerance based on population improvement through recurrent selection (RS).
Audebert, Alain, Châtel, Marc, Grenier, Cécile, Ospina, Yolima, Rodriguez, Francisco   +4 more
core  

Host‐Directed Biomaterials for Combatting Bloodstream Infections: From Macrocyclic Peptides to Immune‐Activating Cell Backpacks

Advanced Functional Materials, EarlyView.
Bloodstream infections (BSI) are one of the leading causes of mortality and morbidity in both civilian and military populations. This paper summarizes recent progress in novel treatment strategies to manage BSI arising from both bacterial and fungal pathogens using molecules, particles, and materials to elicit host‐directed immunity.
Thomas Thomou, Jagadish Krishnappa, Justin B. Schaal, Prasad Tongaonkar, Dat Q. Tran, Wenchao Gu, Yung‐Fu Chang, Michael E. Selsted, Shaoyi Jiang, Samir Mitragotri, Michael Super, Christopher J. Bettinger   +11 more
wiley   +1 more source

Assessing Wheat Traits by Spectral Reflectance: Do We Really Need to Focus on Predicted Trait-Values or Directly Identify the Elite Genotypes Group?

Frontiers in Plant Science, 2017
Phenotyping, via remote and proximal sensing techniques, of the agronomic and physiological traits associated with yield potential and drought adaptation could contribute to improvements in breeding programs. In the present study, 384 genotypes of wheat (
Miguel Garriga, Sebastián Romero-Bravo, Félix Estrada, Alejandro Escobar, Iván A. Matus, Alejandro del Pozo, Cesar A. Astudillo, Gustavo A. Lobos   +7 more
doaj   +1 more source

Augmented reality for high-throughput phenotyping [PDF]

Master of ScienceDepartment of Computer ScienceMitchell NeilsenSmart glasses, like smart phones, have separate operating systems, and can execute many different kinds of software and games.
Wu, Shanshan
core  

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

Advanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz, Jonas De Breuck, Sahar Salehi, Meike N. Leiske   +3 more
wiley   +1 more source