Design automation of microfluidic droplet sorting platforms [PDF]
, 2019 Both basic research and biological design require high throughput screening to parse through the massive amounts of variants generated in experiments. However, the cost and expertise needed for use of such technology limit accessibility.
Densmore, Douglas, McIntyre, David
core
Recent developments in chemoinformatics education [PDF]
, 2001 Chemoinformatics techniques are increasingly being used to analyse the huge volumes of chemical and biological data resulting from combinatorial synthesis and high-throughput screening programmes.
Brown +6 more
core +1 more source
Upscaling the surveillance of tick-borne pathogens in the French Caribbean Islands [PDF]
, 2020 Despite the high burden of vector-borne disease in (sub)tropical areas, few information are available regarding the diversity of tick and tick-borne pathogens circulating in the Caribbean.
Albina, Emmanuel +9 more
core +1 more source
Semiconductor Electronic Label-Free Assay for Predictive Toxicology. [PDF]
, 2016 While animal experimentations have spearheaded numerous breakthroughs in biomedicine, they also have spawned many logistical concerns in providing toxicity screening for copious new materials. Their prioritization is premised on performing cellular-level
Chui, Chi On +5 more
core +2 more sources
Development and validation of a luminescence-based, medium-throughput assay for drug screening in Schistosoma mansoni [PDF]
, 2015 Schistosomiasis, one of the world's greatest neglected tropical diseases, is responsible for over 280,000 human deaths per annum. Praziquantel, developed in the 1970s, has high efficacy, excellent tolerability, few and transient side effects, simple ...
Altamura, Sergio +5 more
core +3 more sources
Natural product libraries: Assembly, maintenance, and screening [PDF]
, 2014 This review discusses successful strategies and potential pitfalls to assembling a natural product-based library suitable for high-throughput screening. Specific extraction methods for plants, microorganisms, and marine invertebrates are detailed, along ...
Butler, Mark S. +2 more
core +1 more source
In Vitro Screening Test Using Leishmania Promastigotes Stably Expressing mCherry Protein [PDF]
, 2014 Transgenic Leishmania major and Leishmania donovani axenic promastigotes constitutively expressing mCherry were used for in vitro antileishmanial drug screening. This method requires minimal sample manipulation and can be easily adapted to automatic drug
Miguel A. Morales, Vacchina, Paola
core +2 more sources
High-throughput screening of encapsulated islets using wide-field lens-free on-chip imaging
, 2018 Islet microencapsulation is a promising solution to diabetes treatment, but its quality control based on manual microscopic inspection is extremely low-throughput, highly variable and laborious.
Alexander, Michael +6 more
core +2 more sources
High-throughput screening with the Eimeria tenella CDC2-related kinase2/cyclin complex EtCRK2/EtCYC3a [PDF]
, 2012 The poultry disease coccidiosis, caused by infection with Eimeria spp. apicomplexan parasites, is responsible for enormous economic losses to the global poultry industry.
Aziz +12 more
core +1 more source
Ranking the stars : a refined Pareto approach to computational materials design [PDF]
, 2013 We propose a procedure to rank the most interesting solutions from high-throughput materials design studies. Such a tool is becoming indispensable due to the growing size of computational screening studies and the large number of criteria involved in ...
Cottenier, Stefaan +2 more
core +2 more sources