Identification of HMGA2 inhibitors by AlphaScreen-based ultra-high-throughput screening assays. [PDF]
Sci Rep, 2020 Su L +15 more
europepmc +1 more source
A High-Throughput Mass Spectrometry Assay Coupled with Redox Activity Testing Reduces Artifacts and False Positives in Lysine Demethylase Screening [PDF]
, 2015 Tim J. Wigle +11 more
openalex +1 more source
Label-Free High-Throughput Screening Assay for the Identification of Norepinephrine Transporter (NET / SLC6A2) Inhibitors [PDF]
, 2021 Hubert J. Sijben +7 more
openalex +1 more source
Plasma‐Treated Hydrogel for Combined RONS and Chemotherapy Delivery: A Proof‐of‐Concept In Ovo
Advanced Functional Materials, EarlyView.This study explores plasma‐treated hydrogels (PTH) as a new way to deliver both reactive oxygen and nitrogen species and chemotherapy (Doxorubicin) directly to tumors. In ovo tests show effects after a single dose, especially in osteosarcoma tumors. Tumor weight decrease, and a resistance‐related protein is reduced.
Milica Živanić +9 more
wiley +1 more source
From emulsion to single-phase microfluidics : an integrated approach to culture and perfusion of multicellular spheroids [PDF]
, 2016 This study presents a novel microfluidic approach for developing large scale screening assays of anticancer compounds on 3D multicellular spheroids.
Boyd, Marie +2 more
core
Recycling of Thermoplastics with Machine Learning: A Review
Advanced Functional Materials, EarlyView.This review shows how machine learning is revolutionizing mechanical, chemical, and biological pathways, overcoming traditional challenges and optimizing sorting, efficiency, and quality. It provides a detailed analysis of effective feature engineering strategies and establishes a forward‐looking research agenda for a truly circular thermoplastic ...
Rodrigo Q. Albuquerque +5 more
wiley +1 more source
Engineering Hybrid Extracellular Vesicles for Functional mRNA Delivery
Advanced Functional Materials, EarlyView.This study optimizes two methods for the generation of extracellular vesicle (EV)‐mimetic‐Lipid Nanoparticle (LNP) (CELLNPs) and EV‐LNP (HEVs) hybrid nanoparticles for messenger (mRNA) delivery. The authors screen lipid compositions to maximize hybrid nanoparticle formation and analyze the resulting nanoparticles with single particle characterization ...
Ana Filipa Louro +6 more
wiley +1 more source
Bright Monocompound Metal Halide Scintillator for Fast Neutron Radiography
Advanced Functional Materials, EarlyView.Metal halide scintillator, tetraphenylphosphonium manganese bromide (TPP2MnBr4), provides a significant benefit for fast neutron imaging. A fourfold increase in efficiency over traditional zinc sulfide screens is achieved by efficiently utilizing neutron interactions within its homogeneous structure.
Aditya Bhardwaj +13 more
wiley +1 more source
High-throughput screening of cellulase F mutants from multiplexed plasmid sets using an automated plate assay on a functional proteomic robotic workcell [PDF]
, 2006 Stephen R. Hughes +7 more
openalex +1 more source