Results 181 to 190 of about 227,287 (224)

High-throughput strategies for monoclonal antibody screening: advances and challenges. [PDF]

J Biol Eng
Wang XD, Ma BY, Lai SY, Cai XJ, Cong YG, Xu JF, Zhang PF.   +6 more
europepmc   +1 more source

mSphere of Influence: High-throughput screens to rapidly assign function to microbial genes. [PDF]

mSphere
Huberman LB.
europepmc   +1 more source

The development of a high-throughput acoustic droplet ejection mass-spectrometry assay and a solid-supported membrane (SSM)-based electrophysiological assay to study the pharmacological inhibition of SLC1-A3, -A2 and -A1 in a drug discovery program. [PDF]

Front Pharmacol
Zuschlag Y, Pommereau A, Warkentin J, Licher T, Bärenz F.   +4 more
europepmc   +1 more source

LPS2336, a New TREK-1 Channel Activator Identified by High Throughput Screening. [PDF]

Biomolecules
Boyer R, Bony R, Maugis M, Schopp J, Leroux M, Michelin C, Gonthier L, Grzeskiewicz Q, Jouannet A, Aissouni Y, Didier B, Gulea M, Girard N, Cintrat JC, Dumeige A, Busserolles J, Ducki S, Lolignier S.   +17 more
europepmc   +1 more source

'Need for speed: high throughput' - mass spectrometry approaches for high-throughput directed evolution screening of natural product enzymes.

Nat Prod Rep
Shepherd RA, Fihn CA, Tabag AJ, McKinnie SMK, Sanchez LM.   +4 more
europepmc   +1 more source

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Immunoproteomics profiling of blood stage Plasmodium vivax infection by high-throughput screening assays.

Journal of Proteome Research, 2010
Completed genome sequences and stage-specific transcriptomes of the intraerythrocytic developmental cycle of Plasmodium vivax offers the opportunity to profile immune responses against P. vivax infection using innovative screening approaches.
Jun-Hu Chen, Jae-Wan Jung, Yue Wang, K. Ha, Feng Lu, C. Lim, S. Takeo, T. Tsuboi, E. Han   +8 more
semanticscholar   +1 more source

Validation of high throughput screening assays against three subtypes of Ca(v)3 T-type channels using molecular and pharmacologic approaches.

Assay and drug development technologies, 2007
T-type Ca(2+) channels encoded by voltage-gated Ca(2+) channel (Ca(v)) 3.1, 3.2, and 3.3 genes play important physiological roles and serve as therapeutic targets for neurological and cardiovascular disorders.
X. Xie, Amy L. Van Deusen, Iuliia Vitko, D. Babu, Lucinda A Davies, Nhung T. Huynh, Holden Cheng, Naibo Yang, P. Barrett, E. Perez-Reyes   +9 more
semanticscholar   +1 more source

High-throughput screening assays to discover small-molecule inhibitors of protein interactions.

Current Drug Discovery Technologies, 2008
The availability of large collections of small-molecule inhibitors of protein interactions would bear a tremendous impact both on academic and therapeutic research.
P. Colas
semanticscholar   +1 more source

Applications of fluorescent polymer superquenching to high throughput screening assays for protein kinases.

Assay and drug development technologies, 2004
Protein kinases are involved in the regulation of cellular metabolism, growth, differentiation, and proliferation. Aberrations in their function can lead to diseases such as cancer and inflammation. Protein kinases are therefore possible targets for drug
Wensheng Xia, F. Rininsland, Shannon K Wittenburg, Xiaobo Shi, K. Achyuthan, D. Mcbranch, D. Whitten   +6 more
semanticscholar   +1 more source

High-Throughput Screening Assays in Toxicology

Methods in Molecular Biology, 2022

semanticscholar   +1 more source