Results 61 to 70 of about 1,074,205 (395)
Hui Jiang1,2 *,* Kefeng Cao3 *,* Chang Fan,1,2 Xiaoya Cui,1,2 Yanzhen Ma,1,2 Jian Liu1 1Experimental Center of Clinical Research, First Affiliated Hospital of Anhui University of Chinese Medicine, Hefei, Anhui, People’s Republic of China; 2School ...
Jiang H +5 more
doaj
Probing the connectivity of neural circuits at single-neuron resolution using high-throughput DNA sequencing [PDF]
There is growing excitement in determining the complete connectivity diagram of the brain—the "connectome". So far, the complete connectome has been established for only one organism, C.
Alex Koulakov +6 more
core +2 more sources
Universal count correction for high-throughput sequencing.
We show that existing RNA-seq, DNase-seq, and ChIP-seq data exhibit overdispersed per-base read count distributions that are not matched to existing computational method assumptions.
Tatsunori B Hashimoto +2 more
doaj +1 more source
ReSeq simulates realistic Illumina high-throughput sequencing data
In high-throughput sequencing data, performance comparisons between computational tools are essential for making informed decisions at each step of a project.
Stephan Schmeing, Mark D. Robinson
doaj +1 more source
Scrutinizing virus genome termini by high-throughput sequencing. [PDF]
Analysis of genomic terminal sequences has been a major step in studies on viral DNA replication and packaging mechanisms. However, traditional methods to study genome termini are challenging due to the time-consuming protocols and their inefficiency ...
Shasha Li +6 more
doaj +1 more source
Deep Sequencing Analysis of RNAs from Citrus Plants Grown in a Citrus Sudden Death-Affected Area Reveals Diverse Known and Putative Novel Viruses. [PDF]
Citrus sudden death (CSD) has caused the death of approximately four million orange trees in a very important citrus region in Brazil. Although its etiology is still not completely clear, symptoms and distribution of affected plants indicate a viral ...
Coletta-Filho, Helvecio D +7 more
core +3 more sources
High-throughput sequencing: a failure mode analysis
Background Basic manufacturing principles are becoming increasingly important in high-throughput sequencing facilities where there is a constant drive to increase quality, increase efficiency, and decrease operating costs.
Marra Marco A +6 more
doaj +1 more source
Efficient COI barcoding using high throughput single-end 400 bp sequencing
Background Over the last decade, the rapid development of high-throughput sequencing platforms has accelerated species description and assisted morphological classification through DNA barcoding. However, the current high-throughput DNA barcoding methods
Chentao Yang +14 more
doaj +1 more source
The study of cell-population heterogeneity in a range of biological systems, from viruses to bacterial isolates to tumor samples, has been transformed by recent advances in sequencing throughput. While the high-coverage afforded can be used, in principle,
A. Wilm +9 more
semanticscholar +1 more source
High-throughput sequencing reveals a simple model of nucleosome energetics
We use nucleosome maps obtained by high-throughput sequencing to study sequence specificity of intrinsic histone-DNA interactions. In contrast with previous approaches, we employ an analogy between a classical one-dimensional fluid of finite-size ...
A. V. Morozov +26 more
core +1 more source

