Results 61 to 70 of about 1,036,014 (384)
Reliable and accurate diagnostics from highly multiplexed sequencing assays [PDF]
, 2020 Scalable, inexpensive, and secure testing for SARS-CoV-2 infection is crucial for control of the novel coronavirus pandemic. Recently developed highly multiplexed sequencing assays (HMSAs) that rely on high-throughput sequencing can, in principle, meet ...
Bloom, Joshua S. +8 more
core
Combined aptamer and transcriptome sequencing of single cells. [PDF]
, 2018 The transcriptome and proteome encode distinct information that is important for characterizing heterogeneous biological systems. We demonstrate a method to simultaneously characterize the transcriptomes and proteomes of single cells at high throughput ...
Abate, Adam R +3 more
core +2 more sources
Microbiome, 2014 Experimental designs that take advantage of high-throughput sequencing to generate datasets include RNA sequencing (RNA-seq), chromatin immunoprecipitation sequencing (ChIP-seq), sequencing of 16S rRNA gene fragments, metagenomic analysis and selective ...
A. Fernandes +5 more
semanticscholar +1 more source
High-Throughput Sequencing and Rare Genetic Diseases [PDF]
Molecular Syndromology, 2012 High-throughput sequencing has drastically changed the research of genes responsible for genetic disorders and is now gradually introduced as an additional genetic diagnostic testing in clinical practice. The current debates on the emerging technical, medical and ethical issues as well as the potential optimum use of the available technology are ...
Makrythanasis P, Antonarakis SE.
openaire +3 more sources
Scrutinizing virus genome termini by high-throughput sequencing. [PDF]
PLoS ONE, 2014 Analysis of genomic terminal sequences has been a major step in studies on viral DNA replication and packaging mechanisms. However, traditional methods to study genome termini are challenging due to the time-consuming protocols and their inefficiency ...
Shasha Li +6 more
doaj +1 more source
Applications in Plant Sciences, 2016 Premise of the study: Using sequence data generated via target enrichment for phylogenetics requires reassembly of high-throughput sequence reads into loci, presenting a number of bioinformatics challenges.
Matthew G. Johnson +7 more
semanticscholar +1 more source
Journal of Inflammation Research, 2021 Hui Jiang1,2 *,* Kefeng Cao3 *,* Chang Fan,1,2 Xiaoya Cui,1,2 Yanzhen Ma,1,2 Jian Liu1 1Experimental Center of Clinical Research, First Affiliated Hospital of Anhui University of Chinese Medicine, Hefei, Anhui, People’s Republic of China; 2School ...
Jiang H +5 more
doaj
Tools for mapping high-throughput sequencing data [PDF]
Bioinformatics, 2012 Abstract Motivation: A ubiquitous and fundamental step in high-throughput sequencing analysis is the alignment (mapping) of the generated reads to a reference sequence. To accomplish this task, numerous software tools have been proposed. Determining the mappers that are most suitable for a specific application is not trivial.
Johan Rung +3 more
openaire +2 more sources
Deep Sequencing Analysis of RNAs from Citrus Plants Grown in a Citrus Sudden Death-Affected Area Reveals Diverse Known and Putative Novel Viruses. [PDF]
, 2017 Citrus sudden death (CSD) has caused the death of approximately four million orange trees in a very important citrus region in Brazil. Although its etiology is still not completely clear, symptoms and distribution of affected plants indicate a viral ...
Coletta-Filho, Helvecio D +7 more
core +3 more sources
Probing the connectivity of neural circuits at single-neuron resolution using high-throughput DNA sequencing [PDF]
, 2011 There is growing excitement in determining the complete connectivity diagram of the brain—the "connectome". So far, the complete connectome has been established for only one organism, C.
Alex Koulakov +6 more
core +2 more sources