Results 41 to 50 of about 16,322,799 (308)

Hepatic transcriptomic analysis of swamp eel (Monopterus albus) fed high-carbohydrate diet supplemented with sodium acetate

, 2023
As the cheapest energy source, the carbohydrate is used in fish feeds to improve physical quality and stimulate protein-sparing action. However, the liver injury usually occurs as the increasing dietary carbohydrate in aquatic animals. Sodium acetate has
Yu, Chuanqi, Yu, C (via Mendeley Data)
core   +2 more sources

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

A high-carbohydrate diet induces greater inflammation than a high-fat diet in mouse skeletal muscle [PDF]

Brazilian Journal of Medical and Biological Research, 2020
We previously reported that both the high-carbohydrate diet (HCD) and high-fat diet (HFD) given for two months promote lipid deposition and inflammation in the liver and brain of mice.
M.M. Antunes, G. Godoy, C.B. de Almeida-Souza, B.A. da Rocha, L.G. da Silva-Santi, L.N. Masi, F. Carbonera, J.V. Visentainer, R. Curi, R.B. Bazotte   +9 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

DIET-INDUCED CHANGES IN SOME PARAMETERS OF OXIDATIVE SATUS IN WISTAR RATS – COMPARISON BETWEEN THREE DIFFERENT DIETS AND EFFECTS OF REPLACING DIETARY SUCROSE WITH STEVIOL GLYCOSIDES

Trakia Journal of Sciences
PURPOSE: The aim of the study was to evaluate the effects of a high-fat diet, high-carbohydrate diet and a combined high-fat high-carbohydrate diet on some parameters of oxidative status in a rat experimental model, and to test the potential positive ...
K. Trifonova
doaj   +1 more source

Adaptive changes in enzyme activity and metabolic pathways in adipose tissue from meal-fed rats

Journal of Lipid Research, 1966
A number of metabolic factors and the activity of a number of enzymes were determined in meal-fed (animals fed a single daily 2 hr meal) and nibbling (ad libitum-fed) rats.
Gilbert A. Leveille, Richard W. Hanson
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Metabolic effects of diets differing in glycaemic index depend on age and endogenous GIP [PDF]

, 2009
Aims/hypothesis High- vs low-glycaemic index (GI) diets unfavourably affect body fat mass and metabolic markers in rodents. Different effects of these diets could be age-dependent, as well as mediated, in part, by carbohydrate-induced stimulation of ...
Isken, Frank, Weickert, Martin O., Pfeiffer, Andreas F. H., Möhlig, Matthias, Abdelrahman, A., Thorens, B., Klaus, Susanne, Nogueiras, R., Tschöp, M. H., Möhlig, M., Isken, F., Tschöp, M.H., Pfeiffer, A.F., Klaus, S., Weickert, M.O.   +14 more
core   +1 more source

Protocol for a randomized controlled trial comparing a very low-carbohydrate diet or moderate-carbohydrate plate-method diet for type 2 diabetes: the LEGEND (Lifestyle Education about Nutrition for Diabetes) trial

Trials, 2023
Background Optimal carbohydrate intake is an important and controversial area in the nutritional management of type 2 diabetes. Some evidence indicates that reducing overall carbohydrate intake with a low- or very low-carbohydrate eating plan can improve
Laura R. Saslow, Adriana Eslamian, Patricia Moran, Wendy Hartogensis, Ashley E. Mason, Sarah Kim, Douglas C. Bauer, Dina Hafez Griauzde, Veronica Goldman, Vivian Liu, Pam Stephens, Kate Raymond, George Yeung, Cindy Leung, Frederick M. Hecht   +14 more
doaj   +1 more source