Results 111 to 120 of about 1,615,493 (360)
Advanced Science, EarlyView.This study constructs a stacked multimodal machine learning model for nonalcoholic fattly liver disease (NAFLD) by integrating genetic and clinical features, and synthesize an in‐silico quantitative marker (ISNLD) that enables personalized risk stratification for intrahepatic and extrahepatic outcomes of high‐risk individuals of NAFLD.
Lushan Xiao +14 more
wiley +1 more source
High-density lipoprotein in chronic renal failure and after renal transplantation. [PDF]
, 1979 Elliott Savdie +3 more
openalex +1 more source
Advanced Science, EarlyView.FfRlpA2, a conserved Fusarium effector, functions as a protease inhibitor by hijacking the E3 ubiquitin ligase IbCHYR1 to degrade the resistance factor IbZnFR, thereby promoting Fusarium pathogenicity. Conversely, the high dosage Pro::IbZnFRHap2 allele was associated with resistance to root rot disease.
Huan Zhang +14 more
wiley +1 more source
Advanced Science, EarlyView.The TALENTs randomized controlled trial evaluates the potential of nucleotides supplementation as an anti‐aging intervention in older adults. After 19 weeks, nucleotides supplementation significantly reduces DNA methylation age, suggesting a delay in epigenetic aging, and improves insulin sensitivity without severe adverse events.
Shuyue Wang +9 more
wiley +1 more source
Journal of Lipid Research, 2019 NMR-based quantification of human lipoprotein (sub)classes is a powerful high-throughput method for medical diagnostics. We evaluated select proton NMR signals of serum lipoproteins for elucidating the physicochemical features and the absolute NMR ...
Daniela Baumstark +8 more
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Interchange of Apolipoproteins between Chylomicrons and High Density Lipoproteins during Alimentary Lipemia in Man [PDF]
, 1973 Richard J. Havel +2 more
openalex +1 more source
Advanced Science, EarlyView.Irisin is a crucial plasma biomarker and promising therapeutic target that reflects disease severity, pulmonary vascular remodeling status and clinical outcome in patients with pulmonary arterial hypertension (PAH). As a novel protective factor, irisin is downregulated in PAH. By ubiquitination, irisin promotes Enolase 1 degradation and suppresses cell
Na Sun +15 more
wiley +1 more source
Lipid-Protein Interactions in High Density Lipoproteins [PDF]
, 1974 Gerd Assmann, H. Bryan Brewer
openalex +1 more source
Advanced Science, EarlyView.Elevated lactate in diabetes activates the GPR132‐Src pathway in macrophages, inducing macrophage senescence and further enhancing foam cell formation. This mechanism exacerbates atherosclerotic progression. Abstract Diabetes is widely acknowledged as a significant risk factor for atherosclerosis, facilitating plaque formation through various ...
Xiaofeng Ge +10 more
wiley +1 more source
A novel approach to measuring macrophage-specific reverse cholesterol transport in vivo in humans
Journal of Lipid Research, 2017 Reverse cholesterol transport (RCT) is thought to be an atheroprotective function of HDL, and macrophage-specific RCT in mice is inversely associated with atherosclerosis.
Marina Cuchel +22 more
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