Results 161 to 170 of about 21,716,016 (301)

Commissioning and Validation of a Synchrocyclotron - Based Ultra-High-Dose-Rate Beamline for FLASH. [PDF]

Int J Part Ther
Lin Y, Setianegara J, Wang A, Gerard N, Nys J, Labarbe R, Traneus E, Gao H, Chen RC.   +8 more
europepmc   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Dose differentiated high-dose-rate prostate brachytherapy: a feasibility assessment of MRI-guided dose escalation to dominant intra-prostatic lesions

Journal of Contemporary Brachytherapy, 2022
Christopher Luminais, Hamidreza Nourzadeh, Eric Aliotta, Kristin Ward, David Cousins, Timothy Showalter, Bruce Libby   +6 more
doaj   +1 more source

A role for eIF5A in translational control of stress‐inducible proteins in multiple myeloma cell lines

Molecular Oncology, EarlyView.
Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both, Ingrid A. M. Derks, Raphaël Vanleyssem, Marine Leclercq, Najla El Hachem, Pierre Close, Eric Eldering, Marco Vincent Haselager   +7 more
wiley   +1 more source

Evaluation of a Faraday cup-style detector as a beam diagnostic system for ultra-high dose rate (FLASH) electron beams. [PDF]

J Appl Clin Med Phys
Lopez A, Baikalov A, Liu K, Esplen N, Bartzsch S, Schüler E.   +5 more
europepmc   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Deciphering Ultra-High Dose Rate Irradiation with <i>Drosophila melanogaster</i>. [PDF]

Antioxidants (Basel)
Kreuzer M, Vetrugno I, Dal Bello R, Tanadini-Lang S, Brunner E, von Salis D, Manetsch D, Tewary S, Guckenberger M, Little J, Pruschy M.   +10 more
europepmc   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Three-dimensional deep learning nomogram for post-plan quality assurance in high-dose-rate prostate brachytherapy. [PDF]

Phys Imaging Radiat Oncol
Beaudry J, Wang T, Enger SA, Damato AL.
europepmc   +1 more source

Prostate external beam radiotherapy combined with high-dose-rate brachytherapy: dose-volume parameters from deformably-registered plans correlate with late gastrointestinal complications

, 2016
Background: Derivation of dose-volume correlated with toxicity for multi-modal treatments can be difficult due to the perceived need for voxel-by-voxel dose accumulation.
Calyn R. Moulton (21294656), Michael J. House (392724), Victoria Lye (3463007), Michele Krawiec (3463016), Colin I. Tang (21294659), Martin A. Ebert (9149663), David J. Joseph (9149651), James W. Denham (21279800)   +7 more
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