Results 21 to 30 of about 2,366,029 (213)
Molecules, 2022 It is reported that Notch3 and mTOR signaling pathways are involved in autophagy, and both can be activated by high glucose (HG). However, the relationship between Notch3 and mTOR and how Notch3 affects mTOR to regulate HG-induced autophagy in bovine ...
Yaocheng Cui +13 more
doaj +1 more source
A Glucose Electrode Using High-Stability Glucose-Oxidase Collagen Membranes [PDF]
Diabetes Care, 1982 A very sensitive glucose electrode was developed using a glucose-oxidase membrane and an anodically polarized platinum disk. Calibration curves were linear over 4.5 concentration decades. It was adapted for human blood samples. The lifetime of glucose-oxidase collagen membranes was greater than 3 yr at 4°C and was ∼6 mo at 20–30°C.
Thevenot, Daniel +2 more
openaire +2 more sources
Silicon-based nanochannel glucose sensor [PDF]
, 2008 Silicon nanochannel biological field effect transistors have been developed for glucose detection. The device is nanofabricated from a silicon-on-insulator wafer with a top-down approach and surface functionalized with glucose oxidase.
Dzyadevich +8 more
core +1 more source
High glucose leads to redistribution of the proteasomal system
BioFactors, 2023 AbstractThe impact of high glucose on the cellular redox state, causing both induction of antioxidative systems and also enhanced protein oxidation is discussed for a long time. It is established that elevated glucose levels are disrupting the cellular proteostasis and influencing the proteasomal system.
Tilman Grune +2 more
openaire +3 more sources
Glucose inhibits cardiac muscle maturation through nucleotide biosynthesis. [PDF]
, 2017 The heart switches its energy substrate from glucose to fatty acids at birth, and maternal hyperglycemia is associated with congenital heart disease. However, little is known about how blood glucose impacts heart formation.
Braas, Daniel +21 more
core +2 more sources
Frontiers in Pharmacology, 2021 Hyperglycemia-induced apoptosis and oxidative stress injury are thought to play important roles in the pathogenesis of diabetic nephropathy (DN). Attenuating high glucose (HG)-induced renal tubular epithelial cell injury has become a potential approach ...
Mengru Ding +21 more
doaj +1 more source
A novel FRET-based screen in high-throughput format to identify inhibitors of malarial and human glucose transporters [PDF]
, 2016 The glucose transporter PfHT is essential to the survival of the malaria parasite Plasmodium falciparum and has been shown to be a druggable target with high potential for pharmacological intervention.
Autry, Joseph M +9 more
core +2 more sources
Effects of breaking up prolonged sitting following low and high glycaemic index breakfast consumption on glucose and insulin concentrations [PDF]
, 2017 Purpose: Breaking up prolonged sitting can attenuate the postprandial rise in glucose and insulin. Whether such effects are dependent of the glycaemic index (GI) of the consumed carbohydrate is unknown.
Bailey, Daniel +4 more
core +3 more sources
Regulation of Transporters for Organic Cations by High Glucose
International Journal of Molecular Sciences, 2023 Endogenous positively charged organic substances, including neurotransmitters and cationic uremic toxins, as well as exogenous organic cations such as the anti-diabetic medication metformin, serve as substrates for organic cation transporters (OCTs) and multidrug and toxin extrusion proteins (MATEs).
Martin Steinbüchel +5 more
openaire +2 more sources
Russian Open Medical Journal, 2020 Aim — To evaluate the effect of ascorbic acid, α-tocopherol, and its combination on the permeability of human umbilical vein endothelial cells (HUVEC’S) culture after high glucose concentration exposure.
Yudi Purnomo +2 more
doaj +1 more source