Results 51 to 60 of about 2,366,029 (213)

Carpinus turczaninowii Extract May Alleviate High Glucose-Induced Arterial Damage and Inflammation

Antioxidants, 2019
Hyperglycemia-induced oxidative stress triggers severe vascular damage and induces an inflammatory vascular state, and is, therefore, one of the main causes of atherosclerosis.
Juhyun Song, So Ra Yoon, Youn Kyoung Son, Woo Young Bang, Chang-Hwan Bae, Joo-Hong Yeo, Hyun-Jin Kim, Oh Yoen Kim   +7 more
doaj   +1 more source

High glucose causes developmental abnormalities in neuroepithelial cysts with actin and HK1 distribution changes

Frontiers in Cell and Developmental Biology, 2023
It has been reported that the offspring of diabetic pregnant women have an increased risk for neural tube defects. Previous studies in animal models suggested that high glucose induces cell apoptosis and epigenetic changes in the developing neural tube ...
Sisi Peng, Sisi Peng, Sisi Peng, Yu Wu, Yu Wu, Yu Wu, Yufang Zheng, Yufang Zheng, Yufang Zheng   +8 more
doaj   +1 more source

High glucose suppresses embryonic stem cell differentiation into cardiomyocytes [PDF]

Stem Cell Research & Therapy, 2016
AbstractBackgroundBabies born to mothers with pregestational diabetes have a high risk for congenital heart defects (CHD). Embryonic stem cells (ESCs) are excellent in vitro models for studying the effect of high glucose on cardiac lineage specification because ESCs can be differentiated into cardiomyocytes.
Yang, Penghua, Chen, Xi, Kaushal, Sunjay, Reece, E. Albert, Yang, Peixin   +4 more
openaire   +2 more sources

In vitro 2-deoxy-2-[18F]fluoro-D-glucose uptake: practical considerations [PDF]

, 2012
In oncology 2-deoxy-2-[F-18]fluoro-D-glucose ([F-18]-FDG), a glucose analogue, is the most used positron emission tomography (PET) tracer. There are however some limitations due to low metabolic activity or high surrounding physiological uptake in ...
Goethals, Ingeborg, Lambert, Bieke, Mees, Gilles, Mertens, Koen, Van De Wiele, Christophe   +4 more
core   +1 more source

Inhibitory Effects of Ecklonia cava Extract on High Glucose-Induced Hepatic Stellate Cell Activation

Marine Drugs, 2011
Nonalcoholic steatohepatitis (NASH) is a disease closely associated with obesity and diabetes. A prevalence of type 2 diabetes and a high body mass index in cryptogenic cirrhosis may imply that obesity leads to cirrhosis. Here, we examined the effects of
Akiko Kojima-Yuasa, Akiko Tamura, Masaki Terada, Isao Matsui-Yuasa, Kumiko Yokogawa   +4 more
doaj   +1 more source

High glucose up-regulates ENaC and SGK1 expression in HCD-cells [PDF]

, 2006
Background/Aim: Diabetic nephropathy is associated with progressive renal damage, leading to impaired function and end-stage renal failure. Secondary hypertension stems from a deranged ability of cells within the kidney to resolve and appropriately ...
Bell LM, Bhargava A, Bland R, Christensen O, Claire Hills, Demerdash TM, Di Paolo S, Hoffman BB, Hong-Long JI, Jeanette Bennett, Khan ZA, Lang F, Lee CT, Lindschau C, Loffing J, Marshall SM, Paul Squires, Pierre Ronco, Prie D, Ricci C, Rosemary Bland, Rossier, Satlin LM, Sharma K, Symonian M, Urbach V, Waldegger S, Wang J, Weigert C, Whiteside CI, Yung S   +30 more
core   +1 more source

New Insights into the Pivotal Role of Iron/Heme Metabolism in TLR4/NF-κB Signaling-Mediated Inflammatory Responses in Human Monocytes

Cells, 2021
Iron metabolism and heme biosynthesis are essential processes in cells during the energy cycle. Alteration in these processes could create an inflammatory condition, which results in tumorigenesis.
Dong Young Kang, Nipin Sp, Eun Seong Jo, Jin-Moo Lee, Kyoung-Jin Jang   +4 more
doaj   +1 more source

Berberine Ameliorates High Glucose-Induced Cardiomyocyte Injury via AMPK Signaling Activation to Stimulate Mitochondrial Biogenesis and Restore Autophagic Flux

Frontiers in Pharmacology, 2018
Background: Type II diabetes (T2D)-induced cardiomyocyte hypertrophy is closely linked to the impairment of mitochondrial function. Berberine has been shown to be a promising effect for hypoglycemia in T2D models.
Weijian Hang, Weijian Hang, Benhong He, Jiehui Chen, Liangtao Xia, Bing Wen, Tao Liang, Xu Wang, Qianying Zhang, Yue Wu, Qingjie Chen, Qingjie Chen, Juan Chen, Juan Chen, Juan Chen   +14 more
doaj   +1 more source

In Vitro investigation of insulin-like growth factor-i and mechano-growth factor on proliferation of neural stem cells in high glucose environment

Neurological Sciences and Neurophysiology, 2023
Objective: High glucose levels cause metabolic and vascular complications by affecting the nervous system with an increased risk of stroke and seizures. There are still no effective treatment modalities for the high morbidity and mortality rates detected
Tugba Aydintug Gurbuz, Çağri Güleç, Fatih Toprak, Selin Fulya Toprak, Selcuk Sozer   +4 more
doaj   +1 more source

Evaluation of Glycated Albumin (GA) and GA/Hba1c Ratio for Diagnosis of Diabetes and Glycemic Control: A Comprehensive Review [PDF]

, 2017
Diabetes Mellitus (DM) is a group of metabolic diseases characterized by chronic high blood glucose concentrations (hyperglycemia). When it is left untreated or improperly managed, it can lead to acute complications including diabetic ketoacidosis and ...
Abdolrahim, Mojgan, Jazayeri, Hossein E., Rabiee, Mohammad, Rajab, Asodollah, Tahriri, Mohammadreza, Tayebi, Lobat, Yazdanpanah, Sara   +6 more
core   +3 more sources