Results 61 to 70 of about 2,366,029 (213)

Determination of the Effect of Thymoquinone on DNA Damage in Kidney Cells Treated to High Glucose Depending on Time and Dosage by Comet Assay

Turkish Journal of Agriculture: Food Science and Technology
The purpose of this study was to assess the anti-genotoxic potential of thymoquinone (TQ) against DNA damage in NRK-52E cells treated with high glucose using the comet assay technique single cell gel electrophoresis method.
Ayşe Usta, Semiha Dede, Veysel Yüksek, Ahmet Cihat Öner   +3 more
doaj   +1 more source

Spectral tracing of deuterium for imaging glucose metabolism. [PDF]

, 2019
Cells and tissues often display pronounced spatial and dynamical metabolic heterogeneity. Common glucose-imaging techniques report glucose uptake or catabolism activity, yet do not trace the functional utilization of glucose-derived anabolic products ...
Liu, Yinong, Miao, Yupeng, Min, Wei, Qian, Naixin, Shen, Yihui, Shi, Lingyan, Wei, Mian, Zhang, Luyuan   +7 more
core  

Insulin and GLP-1 infusions demonstrate the onset of adipose-specific insulin resistance in a large fasting mammal: potential glucogenic role for GLP-1. [PDF]

, 2013
Prolonged food deprivation increases lipid oxidation and utilization, which may contribute to the onset of the insulin resistance associated with fasting.
Crocker, Daniel E, Lee, Andrew, Ortiz, Rudy M, Rodriguez, Ruben, Tavoni, Stephen K, Tift, Michael S, Vazquez-Medina, Jose Pablo, Viscarra, Jose A   +7 more
core   +1 more source

Antioxidant Activity of Cyanidin-3-O-Glucoside and Verbascoside in an in Vitro Model of Diabetic Retinopathy

Frontiers in Bioscience-Landmark, 2022
Background: Reactive oxygen species (ROS) accumulation plays a pivotal role in the onset of cell damage induced by hyperglycemia and represents one of the major factors in the pathogenesis of diabetic retinopathy.
Carmelina Daniela Anfuso, Giovanni Giurdanella, Anna Longo, Alessia Cosentino, Aleksandra Agafonova, Dario Rusciano, Gabriella Lupo   +6 more
doaj   +1 more source

Alginate reduces the increased uptake of cholesterol and glucose in overweight male subjects: a pilot study [PDF]

, 2008
Dietary fibers are of particular interest in the prevention and management of obesity and consequent pathologies. Among the proposed mechanisms of action of fiber is the modulation of nutrient uptake from the small intestine.
Alfieri, Aller, Behall, Behall, Bell, Bernard M. Corfe, Brownlee, Chen, Frias, Gostynski, Goñi, Gray, J.C. Richardson, Jenkins, Jenny R. Paxman, Karmally, Kimura, Lavin, Liu, Peter W. Dettmar, Porcellati, Sandberg, Seal, Strugala, Suka, Torsdottir, Wakabayashi, Williams, Wolf, Wu, Yeomans   +30 more
core   +1 more source

Neural Precursor Cell-Expressed Developmentally Downregulated Protein 4 (NEDD4)-Mediated Ubiquitination of Glutathione Peroxidase 4 (GPX4): A Key Pathway in High-Glucose-Induced Ferroptosis in Corpus Cavernosum Smooth Muscle Cells

Biomolecules
Pharmacological treatment of diabetes mellitus-induced erectile dysfunction (DMED) has become increasingly challenging due to the limited efficacy of phosphodiesterase type 5 inhibitors (PDE5i).
Wenchao Xu, Peng Hu, Jiaxin Wang, Hongyang Jiang, Tao Wang, Jihong Liu, Hao Li   +6 more
doaj   +1 more source

Prolongation of Consciousness in Anoxia of High Altitude by Glucose.

Experimental Biology and Medicine, 1946
Conclusions1. The preflight administration of a single dose of glucose in water to individuals on a normal diet produced a significant increase in the resistance to unconsciousness from anoxia at 27,000 and 30,000 ft. 2. The protection afforded flying personnel by the glucose solution was greater 30 to 50 minutes following its administration than after
A H, RIESEN, T N, TAHMISIAN, C G, MACKENZIE   +2 more
openaire   +2 more sources

Glucose Counteracts Isoprenaline Effects on Ion Channel Functions in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes

Journal of Cardiovascular Development and Disease, 2022
Recent studies indicate that the disorder of glucose metabolism in myocardial tissue is involved in the development of Takotsubo syndrome (TTS). This study investigated the effects of a high level of glucose on the pathogenesis of TTS, focusing on the ...
Lin Qiao, Xuehui Fan, Zhen Yang, Ibrahim El-Battrawy, Xiaobo Zhou, Ibrahim Akin   +5 more
doaj   +1 more source

Hmgcs2 is the hub gene in diabetic cardiomyopathy and is negatively regulated by Hmgcs2, promoting high glucose‐induced cardiomyocyte injury

Immunity, Inflammation and Disease
Background Diabetic cardiomyopathy (DCM) represents a major cause of heart failure and a large medical burden worldwide. This study screened the potentially regulatory targets of DCM and analyzed their roles in high glucose (HG)‐induced cardiomyocyte ...
Ying Wang, Li‐Feng Ping, Fu‐Yan Bai, Xin‐Huan Zhang, Guang‐Hong Li   +4 more
doaj   +1 more source

Lysosomal Ca2+ Signaling Regulates High Glucose-Mediated Interleukin-1β Secretion via Transcription Factor EB in Human Monocytic Cells

Frontiers in Immunology, 2017
Aberrant activation of the innate immune system, including NOD-like receptor pyrin domain containing 3 (NLRP3) inflammasome-dependent interleukin-1β (IL-1β) secretion, has been implicated in the pathogenesis of type 2 diabetes mellitus (T2DM) and its ...
Hisa Hui Ling Tseng, Chi Teng Vong, Yiu Wa Kwan, Simon Ming-Yuen Lee, Maggie Pui Man Hoi   +4 more
doaj   +1 more source