Results 71 to 80 of about 2,366,029 (213)

Camu-Camu Fruit Extract Inhibits Oxidative Stress and Inflammatory Responses by Regulating NFAT and Nrf2 Signaling Pathways in High Glucose-Induced Human Keratinocytes

open access: yesMolecules, 2021
Myrciaria dubia (HBK) McVaugh (camu-camu) belongs to the family Myrtaceae. Although camu-camu has received a great deal of attention for its potential pharmacological activities, there is little information on the anti-oxidative stress and anti ...
Nhung Quynh Do   +10 more
doaj   +1 more source

High glucose enhances store-operated calcium entry by upregulating ORAI/STIM via calcineurin-NFAT signalling [PDF]

open access: yes, 2014
© 2014, Springer-Verlag Berlin Heidelberg. Abstract: ORAI and stromal interaction molecule (STIM) are store-operated channel molecules that play essential roles in human physiology through a coupling mechanism of internal Ca 2+ store to Ca 2+ influx ...
Atkin, Stephen L.   +14 more
core   +1 more source

SUMOylation and deacetylation affect NF-κB p65 activity induced by high glucose in human lens epithelial cells [PDF]

open access: yesInternational Journal of Ophthalmology, 2019
AIM: To explore the effects of IκBα SUMOylation and NF-κB p65 deacetylation on NF-κB p65 activity induced by high glucose in cultured human lens epithelial cells (HLECs).
Xiao Han   +6 more
doaj   +1 more source

PPARδ Inhibits Hyperglycemia-Triggered Senescence of Retinal Pigment Epithelial Cells by Upregulating SIRT1

open access: yesAntioxidants, 2022
Emerging evidence shows that peroxisome proliferator-activated receptor delta (PPARδ) plays a pivotal role in cellular aging. However, its function in retinal disease processes such as hyperglycemia-associated diabetic retinopathy is unclear.
Eun Ji Lee   +7 more
doaj   +1 more source

The Effects of High Haematocrit Levels on Glucose Metabolism Disorders [PDF]

open access: yesJournal of International Medical Research, 2002
There has been only limited research investigating the possible association between raised haematocrit levels, glucose intolerance and type 2 diabetes. In the present study, we explored the association between high haematocrit levels and impaired glucose tolerance by performing oral glucose tolerance tests in 46 patients with chronic obstructive ...
Bektas, Y   +4 more
openaire   +3 more sources

A forage-only diet alters the metabolic response of horses in training [PDF]

open access: yes, 2012
Most athletic horses are fed a high-starch diet despite the risk of health problems. Replacing starch concentrate with high-energy forage would alleviate these health problems, but could result in a shift in major substrates for muscle energy supply from
A. Jansson   +45 more
core   +2 more sources

Hypoxia and hyperglycaemia determine why some endometrial tumours fail to respond to metformin [PDF]

open access: yes, 2020
High expression of Ki67, a proliferation marker, is associated with reduced endometrial cancer-specific survival. Pre-surgical metformin reduces tumour Ki-67 expression in some women with endometrial cancer. Metformin's anti-cancer activity may relate to
Crosbie, EJ   +9 more
core   +2 more sources

Thymol polymeric nanoparticle synthesis and its effects on the toxicity of high glucose on OEC cells: involvement of growth factors and integrin-linked kinase

open access: yesDrug Design, Development and Therapy, 2019
Elahe Karimi,1,2 Shahryar Abbasi,1,3 Naser Abbasi2,41Department of Chemistry, Ilam Branch, Islamic Azad University, Ilam, Iran; 2Biotechnology and Medicinal Plants Research Center, Ilam University of Medical Sciences, Ilam, Iran; 3Department of
Karimi E, Abbasi S, Abbasi N
doaj  

High Glucose Suppresses Keratinocyte Migration Through the Inhibition of p38 MAPK/Autophagy Pathway

open access: yesFrontiers in Physiology, 2019
Wound healing is delayed frequently in patients with diabetes. Proper keratinocyte migration is an essential step during re-epithelialization. Impaired keratinocyte migration is a critical underlying factor responsible for the deficiency of diabetic ...
Lingfei Li   +17 more
doaj   +1 more source

CNS Control of Glucose Metabolism: Response to Environmental Challenges [PDF]

open access: yes, 2013
Over the last 15 years, considerable work has accumulated to support the role of the CNS in regulating postprandial glucose levels. As discussed in the first section of this review, the CNS receives and integrates information from afferent neurons ...
Arble, Deanna M., Sandoval, Darleen A.
core   +1 more source

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