Results 41 to 50 of about 204,374 (297)
Table_1_High Mobility Group Proteins in Sepsis.docx [PDF]
, 2022 Sepsis, a systemic inflammatory response disease, is the most severe complication of infection and a deadly disease. High mobility group proteins (HMGs) are non-histone nuclear proteins binding nucleosomes and regulate chromosome architecture and gene ...
Zhihui He (4558687) +1 more
core +1 more source
Interactions of HMGB Proteins with the Genome and the Impact on Disease
Biomolecules, 2021 High Mobility Group Box (HMGB) proteins are small architectural DNA binding proteins that regulate multiple genomic processes such as DNA damage repair, nucleosome sliding, telomere homeostasis, and transcription.
Calvin K. Voong +2 more
doaj +1 more source
Table_2_High Mobility Group Proteins in Sepsis.docx [PDF]
, 2022 Sepsis, a systemic inflammatory response disease, is the most severe complication of infection and a deadly disease. High mobility group proteins (HMGs) are non-histone nuclear proteins binding nucleosomes and regulate chromosome architecture and gene ...
Zhihui He (4558687) +1 more
core +1 more source
Tumor Biology, 2017 Irinotecan is a natural alkaloid agent widely used in cancer therapy. High-mobility group protein B1 as a non-histone chromosomal protein plays a fundamental role in gene expression and inflammation.
Saeedeh Keyvani-Ghamsari +3 more
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
High Mobility Group Proteins in Tissue Regeneration [PDF]
, 2012 Cartilage damage and treatment thereof are major issues for patients of all ages as well as companion animals such as the dog. The tissue engineering based autologous chondrocyte transplantation (ACT) employs in vitro amplification of explanted ...
Richter, Andreas
core
Biomolecules, 2020 Mitochondrial DNA (mtDNA) molecules are packaged into compact nucleo-protein structures called mitochondrial nucleoids (mt-nucleoids). Their compaction is mediated in part by high-mobility group (HMG)-box containing proteins (mtHMG proteins), whose ...
Veronika Vozáriková +10 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
High-Mobility-Group protein I can modulate binding of transcription factors to the U5 region of the human immunodeficiency virus Type 1 proviral promoter [PDF]
, 2000 HMG I/Y appears to be a multifunctional protein that relies on in its ability to interact with DNA in a structure-specific manner and with DNA, binding transcriptional activators via distinct protein-protein interaction surfaces.
Henderson, A. +4 more
core +1 more source
Biotechnology Reports, 2021 Common carp (Cyprinus carpio) is a commercial fish species valuable for nutritious components and plays a vital role in human healthy nutrition. The SOX (SRY-related genes systematically characterized by a high-mobility group HMG-box) encoded important ...
Imran Zafar +3 more
doaj +1 more source