Results 41 to 50 of about 22,206,764 (294)

Development and validation of high-performance liquid chromatographic method for determination of ofloxacin and lomefloxacin in human plasma [PDF]

open access: yesJournal of the Serbian Chemical Society, 2005
Ahigh-performance liquid chromatographicmethod for the determination of ofloxacin and lomefloxacin in human plasma has been developed and validated. The effect of organic modifiers on the retention of the investigated drugs was investigated.
Zendelovska Dragica, Stafilov Trajče
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Hemoglonbin Typing by High Performance Liquid Chromatography

open access: yesJournal of Associated Medical Sciences, 2015
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Thanusak Tatu, P Kaidkaseam, P Hathirat
doaj  

Chemical components analysis of handmade alcoholic beverages with special focus on psychoactive drugs as adulterants

open access: yesMethodsX
Handmade alcoholic beverages are produced in clandestine laboratories. There are reports concerning the of counterfeit alcoholic beverages adulterated with psychoactive drugs.
Morvarid Sadat Miri   +3 more
doaj   +1 more source

Studi Degradasi Sediaan Infus Ciprofloksasin Menggunakan High Performance Liquid Chromatography

open access: yesJurnal Farmasi Sains dan Praktis, 2016
Penelitian ini menggambarkan perlakuan degradasi infus ciprofloksasin yang dikondisikan dengan pemanasan, penambahan asam dan basa. Produk degradasi dianalisis menggunaan perangkat HPLC merk Waters e2695 Separations, kolom SunFireTM C18, detektor PDA ...
Bekti Nugraheni
doaj   +1 more source

ESI-MS fragmentation pathways of some 1,2,4-triazole-3-thiones, the intermediate compounds in the synthesis of active pharmaceutical ingredients

open access: yesЖурнал органічної та фармацевтичної хімії, 2020
Aim. To determine the fragmentation pathways of eight 1,2,4-triazole-3-thiones, which are intermediate products in the synthesis of active pharmaceutical ingredients of potential and registered pharmaceutical formulations. Results and discussion. HPLC-
Borys O. Varynskyi   +1 more
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

open access: yesFEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui   +4 more
wiley   +1 more source

Fractionation of fecal neutral steroids by high performance liquid chromatography.

open access: yesJournal of Lipid Research, 1985
Fecal neutral steroids were fractionated by high performance liquid chromatography (HPLC) into three major fractions: 5 beta-H, 3-keto steroids; 5 beta-H, 3 beta-hydroxy steroids; and 5 alpha-H and delta 5-3 beta-hydroxy steroids.
E M Jackson   +3 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

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