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High-resolution mass spectrometry for extended PFAS surveillance in food: combining suspect and non-targeted approaches. [PDF]
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High-resolution mass spectrometry for glycoproteomics
Bioanalysis, 2023Tweetable abstract Bottom-up glycoproteomics combined with top-down strategy allows direct analysis of glycoform-mapped glycosylation and its glycans by high-resolution mass spectrometry.
Siyue Bo +5 more
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Mass spectrometry imaging with high resolution in mass and space [PDF]
Histochemistry and Cell Biology, 2013 Mass spectrometry (MS) imaging links molecular information and the spatial distribution of analytes within a sample. In contrast to most histochemical techniques, mass spectrometry imaging can differentiate molecular modifications and does not require labeling of targeted compounds. We have recently introduced the first mass spectrometry imaging method
Andreas Roempp, Bernhard Spengler
exaly +3 more sources
High-Resolution Native Mass Spectrometry
Chemical Reviews, 2022 Native mass spectrometry (MS) involves the analysis and characterization of macromolecules, predominantly intact proteins and protein complexes, whereby as much as possible the native structural features of the analytes are retained. As such, native MS enables the study of secondary, tertiary, and even quaternary structure of proteins and other ...
Albert J.R. Heck +2 more
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Mass microscopy: high-resolution imaging mass spectrometry
Journal of Electron Microscopy, 2010Matrix-assisted laser desorption/ionization (MALDI) imaging mass spectrometry (IMS) is a technique that localizes the spatial distribution of molecules and identifies structures by their molecular mass signatures. Recently, the resolution of MALDI-IMS has been up to microscopic level. MALDI-IMS does not need either separation or purification procedures
Mitsutoshi, Setou, Nobuya, Kurabe
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High resolution field desorption mass spectrometry
Analytica Chimica Acta, 1976Abstract Sulphate esters and sulphate salts of biochemicals and pharmacologically active compounds have been investigated by field desorption mass spectrometry. The underivatized substances gave high cation and cluster ion intensities. Low, but structurally significant, fragmentation was observed.
H.-R. Schulten, W.D. Lehmann
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HIGH-RESOLUTION MASS SPECTROMETRY
1971Mass Spectrometry is unique in the type and amount of information that it can often supply on submicrogram samples. Recent advances include improved understanding of the basic factors affecting ion reaction rates, and application of these in metastable and collision-induced decompositions.
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High resolution mass spectrometry. Bufadienolides—II.
Organic Mass Spectrometry, 1972AbstractComplete low resolution mass spectra and high resolution data for selected important peaks are presented and discussed for a series of naturally occurring 14β, 15β‐epoxybufadienolides (toad poisons) and their derivatives. The compounds examined were resibufogenin, marinobufagin, cinobufagin, desacetylcinobufagin, cinobufotalin ...
Peter Brown +2 more
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Subtyping of the Influenza Virus by High Resolution Mass Spectrometry
Analytical Chemistry, 2009High resolution, high mass accuracy mass spectra of hemagglutinin and whole virus digests of influenza are shown to be able to be used to type and subtype the major circulating forms of the virus in humans. Conserved residues and peptide segments of the hemagglutinin antigen have been identified across type A and B strains, and for type B strains of ...
Downard, Kevin M. +2 more
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High-Resolution Liquid Chromatography–Mass Spectrometry for Lipidomics
2023Liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS) is a powerful tool for identification and classification of lipids. Ultra-high performance liquid chromatography (UHPLC) allows for robust separations of complex mixtures, while high-resolution mass spectrometry (HRMS) identifies compounds with efficiency and accuracy (Zullig T and ...
Faith Christine, Harvey +2 more
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