Results 91 to 100 of about 4,931,974 (307)
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
A New Mechanism of Canopy Effect in Unsaturated Freezing Soils
Canopy effect refers to the phenomenon where moisture accumulates underneath an impervious cover. Field observation reveals that canopy effect can take place in relatively dry soils where the groundwater table is deep and can lead to full saturation of ...
Teng Jidong +3 more
doaj +1 more source
High-speed-propeller wind-tunnel aeroacoustic results [PDF]
Some aerodynamic concepts are presented together with an explanation of how these concepts are applied to advanced propeller design. The unique features of this propulsion system are addressed with emphasis on the design concepts being considered for the
Dittmar, J. H., Jeracki, R. J.
core +1 more source
High speed interferometric ellipsometer
A novel high speed interferometric ellipsometer (HSIE) is proposed and demonstrated. It is based on a novel differential-phase decoder which is able to convert the phase modulation into amplitude modulation in a polarized heterodyne interferometer.
Tsai, C. C. +5 more
openaire +3 more sources
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
A new device for stress monitoring in continuously welded rails using bi-directional strain method
The technology of continuously welded rails (CWRs) is important in modern railway track structures. To measure rail stress, resistance strain gauges are preferred due to their good stability, sensitivity, and resistance to external interference. Based on
Ganzhong Liu +5 more
doaj +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
There has been a lack of precise methods for monitoring and evaluating the entire process of gas fracturing. However, strain monitoring can effectively record the real-time initiation and propagation of cracks. By studying the strain response of borehole
KONG Zixing +5 more
doaj +1 more source
Flexible High Speed Codec (FHSC) [PDF]
The ongoing NASA/Harris Flexible High Speed Codec (FHSC) program is described. The program objectives are to design and build an encoder decoder that allows operation in either burst or continuous modes at data rates of up to 300 megabits per second. The
Segallis, G. P., Wernlund, J. V.
core +1 more source
The role of histone modifications in transcription regulation upon DNA damage
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source

