Results 121 to 130 of about 7,826,326 (312)

High temperature insulation barrier composite [PDF]

, 1989
A composite material suitable for providing insulation for the nozzle structure of the Space Shuttle and other similar surfaces is disclosed. The composite layer is comprised of an outer skin layer of nickel chromium and an interleaved inner region ...
Onstott, Joseph W.
core   +1 more source

Strong Pinning in High Temperature Superconductors

, 2002
Detailed measurements of the critical current density jc of YBa2Cu3O7 films grown by pulsed laser deposition reveal the increase of jc as function of the filmthickness.
A. Abal’oshev, A. Catana, A. I. Larkin, A. Schönenberger, A. Wahl, B. Dam, B. Dam, B. Dam, B. Roas, C. J. Liu, C. J. van der Beek, C. J. van der Beek, Ch. Gerber, Ch. Jooss, D. R. Nelson, D. R. Nelson, E. H. Brandt, E. Sheriff, F. C. Klaassen, F. C. Klaassen, G. Blatter, G. Kästner, I. Abalosheva, I. Abal’osheva, J. Gilchrist, J. Pearl, K. Verbist, L. A. Dorosinskiĭ, M. Hawley, M. Konczykowski, M. Konczykowski, M. V. Feigel’man, M. V. Feigel’man, M. V. Indenbom, P. Gierlowski, P. H. Kes, P. H. Kes, R. Griessen, R. Prozorov, S. Barbanera, S. J. Lewandowski, S. Kokkaliaris, T. I. Selinder, V. Hardy, V. M. Vinokur, Yu. N. Ovchinnikov   +45 more
core   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Advanced high-temperature electromagnetic pump [PDF]

, 1972
Three phase helical, electromagnetic induction pump for use as boiler feed pump in potassium Rankine-cycle power system is described. Techniques for fabricating components of pump are discussed.
Gahan, J. W., Powell, A. H.
core   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

High-temperature mixer development [PDF]

High temperature mixer development - Heat and mechanical load tests conducted on mockup of solar simulator ...
Lorell, K. R.
core   +1 more source

The High Temperature Superconductivity in Cuprates

, 2012
We discuss the high-temperature superconductivity in copper oxide ceramics. We propose an effective Hamiltonian to describe the dynamics of electrons or holes injected into the copper oxide layers.
Cea, Paolo
core   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source