Results 41 to 50 of about 109,071 (235)
The role and implications of mammalian cellular circadian entrainment
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
By application of a horizontal magnetic field, BH, with 0.3% against a toroidal magnetic field, BT, electron cyclotron wall conditioning (ECWC) plasmas produced by 2nd-harmonic X-mode (X2-mode) EC waves expand radially toward the inner wall, which is to ...
Masakatsu Fukumoto +5 more
doaj +1 more source
Higher-order conditioning of fear (CER) [PDF]
Stable higher-order conditioning of an emotional response was found in a vast majority of rats given an extension of the CER suppression procedure. The phenomenon was demonstrated under a variety of conditions and frequently took the the form of total suppression in the presence of a stimulus which had never been paired with shock.
openaire +1 more source
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Literation Skill to Improve Higher-Order Thinking Skills in Elementary School Students
Higher-order thinking skill is closely related to literacy skills. However, data from PIRLS 2011 states that the reading ability of elementary school students in Indonesia is relatively low because it is ranked 42 out of 45 countries. Data from PISA 2018,
Husni Mubarok, Dian Mustika Anggraini
doaj +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
The function of parallel neural processing is a fundamental problem in Neuroscience, as it is found across sensory modalities and evolutionary lineages, from insects to humans.
Julie eCarcaud +3 more
doaj +1 more source
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Do personality traits predict individual differences in excitatory and inhibitory learning?
Conditioned inhibition (CI) is demonstrated in classical conditioning when a stimulus is used to signal the omission of an otherwise expected outcome. This basic learning ability is involved in a wide range of normal behaviour - and thus its disruption ...
Zhimin eHe +3 more
doaj +1 more source

