Results 71 to 80 of about 249,450 (296)

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Studies on Higher Alcohols. II.

Journal of Japan Oil Chemists' Society, 1963
Known mixtures of fatty alcohol acetates were separated into the saturated, monoenoic, dienoic and trienoic components by the thin-layer chromatography using mercuric acetate adduct method and silver nitrate-silicic acid method. Sample alcohol acetates were as follows;1. Steary 1 alcohol acetate. 2. Oleyl alcohol acetate. 3. Linoleyl alcohol acetate. 4.
Akira HASHIMOTO, Katsunori MUKAI
openaire   +2 more sources

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

The Formation of Aroma Compounds During Fermentation in Relation to Yeast Nutrient Source in Sauvignon Blanc Wine

Fermentation
This study aimed to determine the effects of diammonium phosphate (DAP) and yeast autolysates (organic nutrients) added during alcoholic fermentation on the content and profile of aroma compounds in Sauvignon Blanc wines.
Zorica Lelova Temelkova, Helena Baša Česnik, Andreja Vanzo, Klemen Lisjak   +3 more
doaj   +1 more source

Biological evaluation and molecular modelling of didanosine derivatives [PDF]

, 2014
Five carbonate derivatives of 50-O-20,30-dideoxyinosine (DDI, 1) have been synthesized by combination with aliphatic alcohols, with their in vitro anti-HIV activity and cytotoxicity being evaluated afterward in human peripheral blood mononuclear cells ...
Briñon, Margarita Cristina, de Candia, Cristian Ariel, Gualdesi, María Soledad, Pampuro, Sandra Esther, Quevedo, Mario Alfredo, Ravetti, Soledad, Turk, Gabriela Julia Ana   +6 more
core   +1 more source

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

FEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng, Souvik Datta, Derrick R. Samuelson   +2 more
wiley   +1 more source

THE CHANGES IN THE CONTENT OF ALIPHATIC ALCOHOLS IN BARLEY SEEDLINGS UNDER THE INFLUENCE OF AN ULTRAHIGH FREQUENCY ELECTROMAGNETIC FIELD

Известия высших учебных заведений. Поволжский регион: Естественные науки, 2020
Background. Higher fatty alcohols are a valuable raw material for pharmacology and can serve as an adaptogen in crop production, reducing post-stress effects in the cultivation of crops. Policosanols are linear saturated aliphatic alcohols with carbon
O. M. Soboleva, E. P. Kondratenko, A. S. Sukhikh, M. G. Kurbanova   +3 more
doaj   +1 more source

Investigating Interactions of Biomembranes and Alcohols: A Multiscale Approach

, 2004
We study the interaction of lipid bilayers with short chain alcohols using molecular dynamics on different length scales. We use detailed atomistic modeling and modeling on the length scale where an alcohol is just an amphiphilic dimer.
Adachi, Ayton, Balali-Mood, Bandyopadhyay, Bemporad, Berendsen, Berendsen, Berger, Bisson, Cramer, de Vries, Essmann, Falck, Faller, Feller, Feller, Goetz, Guo, Gurtovenko, Husslein, Kranenburg, Lee, Leontiadou, Lindahl, Ly, Ly, Marrink, Marrink, Mashl, Mou, Mouritsen, Müller, Nagle, Pandit, Pandit, Patra, Patra, Patra, Pereira, Rog, Saiz, Shelley, Smit, Smondryev, Smondryev, Soddemann, Sum, Sum, Tieleman, Tobias, Tu   +50 more
core   +1 more source

Studies on the Higher Fatty Alcohols

Journal of the agricultural chemical society of Japan, 1952
1) Unsaturated-long chain fatty alcohols were prepared in good yield by the reduction of cotton-seed and poppy-seed oils with sodium and ethylene glycol monoethyl ether (Cellosolve) in toluene. 2) These alcohols were fractionated by vacuum distillation and characterized by the deter-mination of iodine and hydroxyl values.
openaire   +6 more sources

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source