Results 91 to 100 of about 2,685,365 (305)

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

UNIVERSIDADE NO SÉCULO XXI: PESQUISA E ENSINO

open access: yesRevista Gestão Universitária na América Latina, 2012
The aim of this article is to discuss the validity of public policies adopted by the Brazilian government in relation to higher education during the last decade.
Martha Abrahão Saad Lucchesi   +1 more
doaj  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Transformation through technology-enhanced learning in Australian higher education

open access: yes, 2009
The application of technology-enhanced learning and the global Internet has stimulated some transformation of higher education in most Australian institutions.
Postle, Glen   +2 more
core   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Preparing for Higher Education Studies: Survey of Bachelor Level Students, January - May, 2017

open access: yes, 2022
The purpose of the study: to investigate the attitude of bachelor students towards higher education maturity and to identify the factors influencing the quality of higher education maturity in Lithuania.
Research and Higher Education Monitoring and Analysis Centre
core  

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

A study of integration the information and communication technologies (ICT) in scientific activities of students in Isfahan University: Faculties of Educational science, Engineering and Science [PDF]

open access: yesرویکردهای نوین آموزشی, 2013
The main purpose of the present study was to investigate how new technologies were integrated in educational and research programs of Isfahan University students.
Z. Aghabasiri, B. Zamani
doaj  

Higher education service learning with First Peoples of Australia [PDF]

open access: yes, 2015
Australian higher education institutions face increasing pressure to institute Aboriginal and Torres Strait Islander culture at every level of activity.
Sunderland, Naomi   +7 more
core  

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