Results 101 to 110 of about 2,685,365 (305)

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Processus de problématisation et mobilisation de la forme « problème » dans les pédagogies des écoles d’ingénieurs : une analyse de cas par les capabilités

Recherches en Éducation
Active pedagogy methods refer to a set of educational approaches that aim to put learners in a position where they actively engage in their own learning processes.
Sarah Guez, Solveig Fernagu, Céline Viazzi   +2 more
doaj   +1 more source

Fall enrollment in higher education.

Mode of access: Internet.Continues: National Center for Education Statistics.
National Center for Education Statistics.
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Higher education export service delivery by the University of Stellenbosch [PDF]

International trade in higher education services provides opportunities for stimulating economic development and fostering the mobility of knowledge, leading to increased intellectual capital, which is vital for a country to remain competitive in a ...
Emile du Plessis
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In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Empowering student-led initiatives: integrating social action into higher education curriculum in West Java

Perspectives in Education
This article presents a comprehensive examination of a pioneering social action endeavor led by first-year bachelor and vocational students in Sumedang, West Java.
Erli Sarilita, Nani Murniati, Harmas Yazid Yusuf   +2 more
doaj   +1 more source

Past, Present and Future: Acknowledging Indigenous Achievement and Aspiration in Higher Education [PDF]

, 2017
The number of Indigenous students enrolled in higher education is increasing. Yet parity with the proportion of domestic students attending university remains some way off.
Trudgett, M, Page, S, Sullivan, Corrinne (R19343), Sullivan, C, Page, Susan (R20436), Trudgett, Michelle (R19725)   +5 more
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CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

World university rankings 2015-2016

, 2015
The Times Higher Education World University Rankings 2015-2016 list the best global universities and are the only international university performance tables to judge world class universities across all of their core missions - teaching ...
Times Higher Education
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