Results 111 to 120 of about 2,685,365 (305)

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Higher Education Outcomes, Graduate Employment and University Performance Indicators [PDF]

Official employment-related Performance Indicators in UK Higher Education are based on the population of students responding to the First Destination Supplement (FDS).
Bratti, Massimiliano, McKnight, Abigail, Smith, Jeremy, Naylor, Robin   +3 more
core  

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

‘To strive, to seek, to find, and not to yield’

Transylvanian Review of Administrative Sciences
This essay explores the essential role of univer­sities in modern society, emphasizing their need to transcend isolation and actively engage with their communities.
Diana Camelia Iancu
doaj   +1 more source

Development of inclusive higher education at pedagogical universities

Perspectives of science and Education
Introduction. The development of inclusive higher education in the world community takes place through various models: desegregation, mainstreaming, integration, and inclusion. The latter is focused on reforming the higher school, creating an accessible educational environment, and developing an inclusive culture at higher educational establishments
Vericheva, Olga N., Suiunalieva, Burulsun Sh., Toktorbekova, Nurzyinat A., Ivanova, Tatyana S.   +3 more
openaire   +1 more source

Finland–EU higher education policy network: Structure, formation, and characteristics

This introduction sets the premise for researching European Union (EU)–Finland networks in the context of higher education policymaking. It discusses our ontological assumptions concerning the dynamics of knowledge use and production in higher education ...
Eeva, Katri, Saarinen, Paula, Kallunki, Jarmo   +2 more
core   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Records of the University Of Melbourne Centre For The Study Of Higher Education

, 1969
This record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete.
University Of Melbourne. Centre For The Study Of Higher Education
core  

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Knowledge, power, and networks in higher education policymaking

This introduction sets the premise for researching European Union (EU)–Finland networks in the context of higher education policymaking. It discusses our ontological assumptions concerning the dynamics of knowledge use and production in higher education ...
Eeva, Katri, Kauko, Jaakko
core   +1 more source