Results 111 to 120 of about 99,672 (347)

Characterization of spatiotemporal and kinetic gait variables in dogs with hindlimb ataxia and bilateral hindlimb lameness

BMC Veterinary Research
Abstract Background Discriminating the underlying cause of gait abnormalities can be challenging in a clinical setting, especially in the presence of bilateral disease. Pressure-sensitive walkways (PSWs) have been utilized to characterize the gait of dogs with various neurologic or orthopaedic conditions.
Clair Park, Dominique M. Sawyere, Theresa E. Pancotto, Otto I. Lanz, Stephen R. Werre   +4 more
openaire   +3 more sources

Effects of resveratrol on the recovery of muscle mass following disuse in the plantaris muscle of aged rats. [PDF]

PLoS ONE, 2013
Aging is associated with poor skeletal muscle regenerative ability following extended periods of hospitalization and other forms of muscular disuse. Resveratrol (3,5,4'-trihydroxystilbene) is a natural phytoalexin which has been shown in skeletal muscle ...
Brian T Bennett, Junaith S Mohamed, Stephen E Alway   +2 more
doaj   +1 more source

Wireless In Situ Catalytic Electron Signaling‐Mediated Transcriptomic Reprogramming for Neuron Regeneration via Adaptable Antennas

Advanced Science, EarlyView.
A wireless‐charging sustained oxygen release from conductive microgels (SOCO) served as an antenna and an on‐demand O2 release for nerve regeneration is developed. Introducing “electromagnetic messenger”, using external alternating magnetic field (AMF) to enhance catalytic oxygen release and electrical stimulation to promote the reconstruction of blood
Hoi Man Iao, Chih‐Ying Chen, Ya‐Hui Lin, Wan‐Chi Pan, Chun‐Yi Liang, Hsiu‐Ching Liu, Lo‐Jei Ching, Pei‐Yu Weng, Min‐Ren Chiang, Ru‐Siou Hsu, Tsu‐Chin Chou, I‐Chi Lee, Lun‐De Liao, Li‐An Chu, Shih‐Hwa Chiou, Shang‐Hsiu Hu   +15 more
wiley   +1 more source

VASCULAR DOPAMINE RECEPTORS IN THE CANINE HINDLIMB [PDF]

British Journal of Pharmacology, 1975
Increases in femoral blood flow were produced by intra‐arterial injections of dopamine (5–50 μg) in some but not all anaesthetized dogs studied, following treatment with the α‐adrenoceptor antagonist, phentolamine. The dilator effect of dopamine was not due to inhibition of adrenergic vasomotor tone as it was not affected by pharmacological procedures
R. Padanyi, Christopher Bell, W.J. Lang, Elizabeth L Conway   +3 more
openaire   +3 more sources

Astrocytic ET‐1 System Determines Microglia Phenotype Following Spinal Cord Injury

Advanced Science, EarlyView.
The study reveals that astrocytic ET‐1 system is solely activated by thrombin following SCI via RhoA/NF‐κB and MAPKs/NF‐κB signal pathway. The release of astrocytic ET‐1 drives microglia polarization toward M1 phenotype through YAP signaling via ETA and ETB receptors.
Bingqiang He, Si Xu, Mengdi Li, Hui Li, Shaolan Li, Li Niu, Honghua Song, Rixin Cai, Yue Zhou, Zhilong Cao, Yingjie Wang, Yongjun Wang   +11 more
wiley   +1 more source

An Efficient Heat and Peroxynitrite Generating Nanoplatform for Multimodal Imaging‐guided Precision Tumor Phototherapy

Aggregate, EarlyView.
Reported herein is the rational‐designed aggregation‐induced emission molecule (BPT), its nanoparticles (BPT NPs), and further processed heat and peroxynitrite generating nanoplatform for precision multimodal imaging‐guided tumor phototherapy. This nanoplatform showed near‐infrared II fluorescence, photothermal, and photoacoustic imaging capabilities ...
Ziyi Xu, Mingkun Lv, Jingkai Yang, Tingting Li, Jiahui Lv, Jiaxin Li, Hongjun Xiao, Yicheng Yang, Siyu Zhou, Xuan Tan, Li Cheng, Heng Guo, Lei Xi, Pan‐Lin Shao, Bo Zhang   +14 more
wiley   +1 more source

Endothelial cell-by-cell profiling reveals the temporal dynamics of VEGFR1 and VEGFR2 membrane localization after murine hindlimb ischemia.

American Journal of Physiology. Heart and Circulatory Physiology, 2013
VEGF receptor (VEGFR) cell surface localization plays a critical role in transducing VEGF signaling toward angiogenic outcomes, and quantitative characterization of these parameters is critical to advancing computational models for predictive medicine ...
P. Imoukhuede, A. Dokun, B. Annex, A. Popel   +3 more
semanticscholar   +1 more source

SAGE profiling of the forelimb and hindlimb.

Genome biology, 2002
A recent study has used serial analysis of gene expression to compare mouse forelimb and hindlimb gene-expression profiles. The method successfully identified known regulators of limb identity and has generated a candidate set of differentially expressed genes that may regulate limb identity.
openaire   +3 more sources

A Laser-Guided Spinal Cord Displacement Injury in Adult Mice [PDF]

, 2018
Mouse models are unique for studying molecular mechanisms of neurotrauma because of the availability of various genetic modified mouse lines. For spinal cord injury (SCI) research, producing an accurate injury is essential, but it is challenging because ...
Bakare, Adewale A., Fry, Collin M.E., Qu, Wenrui, Shields, Christopher B., Shields, Lisa B.E., Wu, Xiangbing, Xu, Xiao-Ming, Zhang, Yi Ping   +7 more
core   +1 more source

Morphological diversity of saber‐tooth upper canines and its functional implications

The Anatomical Record, EarlyView.
Abstract Elongated upper canine teeth, commonly known as saber‐teeth, have evolved three times within the sub‐order Feliformia. The species that wielded them flourished throughout the Cenozoic and have historically been separated into two morphological groups: the dirk‐tooths with longer, flatter canines, and the scimitar‐tooths with shorter, serrated ...
Caitlin D. Shelbourne, Stephan Lautenschlager   +1 more
wiley   +1 more source