Results 41 to 50 of about 99,672 (347)

Identification of Transcription Factor Networks during Mouse Hindlimb Development

Cells, 2022
Mammalian hindlimb development involves a variety of cells and the regulation of spatiotemporal molecular events, but regulatory networks of transcription factors contributing to hindlimb morphogenesis are not well understood.
Maochun Wang, Ruiyang Jiang, Guihua Tan, Zizheng Liu, Chen Tang, Rui Wu, Dongquan Shi   +6 more
doaj   +1 more source

Ipsilesional Motor Cortex Plasticity Participates in Spontaneous Hindlimb Recovery after Lateral Hemisection of the Thoracic Spinal Cord in the Rat

Journal of Neuroscience, 2018
After an incomplete spinal cord injury (SCI) spontaneous motor recovery can occur in mammals, but the underlying neural substrates remain poorly understood.
Andrew R. Brown, Marina Martinez
semanticscholar   +1 more source

Functional limb muscle innervation prior to cholinergic transmitter specification during early metamorphosis in Xenopus

eLife, 2018
In vertebrates, functional motoneurons are defined as differentiated neurons that are connected to a central premotor network and activate peripheral muscle using acetylcholine.
Francois M Lambert, Laura Cardoit, Elric Courty, Marion Bougerol, Muriel Thoby-Brisson, John Simmers, Hervé Tostivint, Didier Le Ray   +7 more
doaj   +1 more source

Inhibiting myostatin signaling partially mitigates structural and functional adaptations to hindlimb suspension in mice

npj Microgravity, 2023
Novel treatments for muscle wasting are of significant value to patients with disease states that result in muscle weakness, injury recovery after immobilization and bed rest, and for astronauts participating in long-duration spaceflight.
Andrea M. Hanson, Mary H. Young, Brooke C. Harrison, Xiaolan Zhou, H. Q. Han, Louis S. Stodieck, Virginia L. Ferguson   +6 more
doaj   +1 more source

Muscle moment arms and sensitivity analysis of a mouse hindlimb musculoskeletal model

Journal of Anatomy, 2016
Musculoskeletal modelling has become a valuable tool with which to understand how neural, muscular, skeletal and other tissues are integrated to produce movement. Most musculoskeletal modelling work has to date focused on humans or their close relatives,
James P. Charles, O. Cappellari, A. Spence, D. Wells, J. Hutchinson   +4 more
semanticscholar   +1 more source

Cancellous bone and theropod dinosaur locomotion. Part III—Inferring posture and locomotor biomechanics in extinct theropods, and its evolution on the line to birds [PDF]

, 2018
This paper is the last of a three-part series that investigates the architecture of cancellous bone in the main hindlimb bones of theropod dinosaurs, and uses cancellous bone architectural patterns to infer locomotor biomechanics in extinct non-avian ...
Abourachid, Alexander, Allen, Allen, Allmendinger, Attene, Bakker, Bates, Bates, Bates, Bates, Beer, Benson, Biewener, Biewener, Biewener, Bishop, Bishop, Bishop, Bishop, Bishop, Blob, Brochu, Brusatte, Butcher, Campione, Cardozo, Carrano, Carrano, Carrano, Carrano, Christiansen, Christiansen, Clack, Dececchi, Delp, Farlow, Farlow, Fujiwara, Gao, Gatesy, Gatesy, Gatesy, Gatesy, Gatesy, Gatesy, Gatesy, Gatesy, Gatesy, Gatesy, Gatesy, Gatesy, Gilmore, Heers, Henderson, Henderson, Holtz, Horner, Hotton, Hutchinson, Hutchinson, Hutchinson, Hutchinson, Hutchinson, Hutchinson, Hutchinson, Hutchinson, Hutchinson, Hutchinson, Hutchinson, Hutchinson, Hutchinson, Jacobson, Johnson, Kambic, Kambic, Keller, Kemp, Lai, Lambe, Lautenschlager, Lee, Marsh, Martelli, McCrea, Molnar, Norell, Norell, Osborn, Ostrom, Paul, Pauwels, Pierce, Pittman, Rauhut, Reilly, Roberts, Rubenson, Russell, Sellers, Sellers, Snively, Stevens, Taylor, Thewissen, Thulborn, Tsai, Tsai, Tsuihiji, Unwin, Valente, Van Der Reest, Villette, Wall-Scheffler, Wilson, Xu, Xu, Zelenitsky   +117 more
core   +2 more sources

DNase I and Sivelestat Ameliorate Experimental Hindlimb Ischemia-Reperfusion Injury by Eliminating Neutrophil Extracellular Traps

Journal of Inflammation Research, 2023
Chun-Lian Wang,1 Yan Wang,2 Qi-Lan Jiang,3 Yang Zeng,4 Qing-Ping Yao,5 Xing Liu,6 Tao Li,7 Jun Jiang1 1Department of General Surgery (Thyroid Surgery), The Affiliated Hospital of Southwest Medical University, Luzhou, People’s Republic of China ...
Wang CL, Wang Y, Jiang QL, Zeng Y, Yao QP, Liu X, Li T, Jiang J   +7 more
doaj  

Cordymin alleviates osteoporosis induced by hindlimb unloading via regulating the gut - microelements -bone axis --for non-clinical studies

BMC Musculoskeletal Disorders, 2023
Introduction The purpose of this study was to evaluate the protective effects of cordymin on osteoporosis induced by hindlimb unloading(HLU) in rats and whether cordymin can prevent bone loss from HLU.
Wei Qi, Tiancheng Ma, Yufei Ji, Hong Jia, Qiang Sun, Dawei Zhang   +5 more
doaj   +1 more source

Mesenchymal Stem Cells Enhance Nerve Regeneration in a Rat Sciatic Nerve Repair and Hindlimb Transplant Model

Scientific Reports, 2016
This study investigates the efficacy of local and intravenous mesenchymal stem cell (MSC) administration to augment neuroregeneration in both a sciatic nerve cut-and-repair and rat hindlimb transplant model.
D. Cooney, E. Wimmers, Z. Ibrahim, J. Grahammer, Joani M. Christensen, G. Brat, Lehao Wu, K. Sarhane, Joseph, Lopez, C. Wallner, Georg J. Furtmüller, N. Yuan, J. Pang, K. Sarkar, W. P. A. Lee, G. Brandacher   +16 more
semanticscholar   +1 more source

Continuous infusion of an agonist of the tumor necrosis factor receptor 2 in the spinal cord improves recovery after traumatic contusive injury. [PDF]

, 2019
AimThe activation of the TNFR2 receptor is beneficial in several pathologies of the central nervous system, and this study examines whether it can ameliorate the recovery process following spinal cord injury.MethodsEHD2-sc-mTNFR2 , an agonist specific ...
Bethea, John R, Blumenthal, Gary H, Bracchi-Ricard, Valerie, Fischer, Roman, Gerald, Marcus J, Kontermann, Roland E, Moxon, Karen A, Nandakumar, Bharadwaj, Pfizenmaier, Klaus, Ricard, Jerome, Williams, Raushaun   +10 more
core   +2 more sources