Results 21 to 30 of about 13,123 (252)

Hyperthermic intraperitoneal chemotherapy (HIPEC) plus systemic chemotherapy versus systemic chemotherapy alone in locally advanced gastric cancer after D2 radical resection: a randomized-controlled study

Journal of Cancer Research and Clinical Oncology, 2023
Currently, there is a lack of an effective strategy for the prevention of peritoneal metastasis (PM) from locally advanced gastric cancer (AGC). This randomized-controlled study aimed to evaluate the outcome of D2 radical resection with hyperthermic ...
P. Yu, Xingmao Huang, Ling Huang, G. Dai, Qi Xu, Jingquan Fang, Z. Ye, Tengjiao Chai, Yi-an Du   +8 more
semanticscholar   +1 more source

Lobaplatin-based prophylactic hyperthermic intraperitoneal chemotherapy for T4 gastric cancer patients: A retrospective clinical study

Frontiers in Oncology, 2023
ObjectiveTo explore the clinical efficacy of lobaplatin-based prophylactic hyperthermic intraperitoneal chemotherapy (HIPEC) for patients with T4 gastric cancer after surgery and to evaluate its impact on survival.Materials and methodsData on patients ...
Yuxin Zhong, Wenzhe Kang, Haitao Hu, Weikun Li, Jing Zhang, Yantao Tian   +5 more
doaj   +1 more source

Single versus multiple hyperthermic intraperitoneal chemotherapy applications for T4 gastric cancer patients: Efficacy and safety profiles

Frontiers in Oncology, 2023
ObjectiveTo explore the clinical safety and efficacy of single and multiple applications of lobaplatin-based hyperthermic intraperitoneal chemotherapy (HIPEC) for patients with T4 gastric cancer and to evaluate the impact of HIPEC on peritoneal ...
Jing Zhang, Yuemin Sun, Xiaofeng Bai, Peng Wang, Liang Tian, Yantao Tian, Yuxin Zhong   +6 more
doaj   +1 more source

GECOP-MMC: phase IV randomized clinical trial to evaluate the efficacy of hyperthermic intraperitoneal chemotherapy (HIPEC) with mytomicin-C after complete surgical cytoreduction in patients with colon cancer peritoneal metastases

BMC Cancer, 2022
Background The French PRODIGE 7 trial, published on January 2021, has raised doubts about the specific survival benefit provided by HIPEC with oxaliplatin 460 mg/m 2 (30 minutes) for the treatment of peritoneal metastases from colorectal cancer. However,
Fernando Magno Quintão Pereira, Á. Serrano, I. Manzanedo, E. Pérez-Viejo, S. González-Moreno, L. González-Bayón, Á. Arjona-Sánchez, J. Torres, I. Ramos, M. E. Barrios, P. Cascales, R. Morales, E. Boldo, A. García-Fadrique, X. Arteaga, A. Gutiérrez-Calvo, S. Sánchez-García, E. Asensio, Cesar P. Ramírez, M. Artiles, J. Vaqué, P. A. Parra, P. Villarejo, Cristóbal Muñoz-Casares, E. Turienzo, A. Calero, I. J. Torrejimeno, I. Prieto, J. Galindo, Vicente Borrego, Manuel E. Marcello, C. Rihuete, J. Carrasco, L. Gómez-Quiles   +33 more
semanticscholar   +1 more source

Therapeutic Value of Hyperthermic Intraperitoneal Chemotherapy on Non-radical Appendiceal Low-grade Pseudomyxoma Peritonei

Zhongliu Fangzhi Yanjiu, 2020
Objective To explore the application value of hyperthermic intraperitoneal chemotherapy(HIPEC) on non-radical appendiceal low-grade pseudomyxoma peritonei(PMP).
SHI Guanjun, XIA Ao, AN Lubiao, ZHAI Xichao, MA Ruiqing, LU Yiyan, PANG Shaojun, CAI Ying, WANG Bing, CHEN Feng, XU Hongbin   +10 more
doaj   +1 more source

The Role of Prophylactic and Adjuvant Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in Prevention of Peritoneal Metastases in Advanced Colorectal Cancer

Journal of Clinical Medicine, 2023
Hyperthermic intraperitoneal chemotherapy (HIPEC) is a locoregional therapy that may be combined with cytoreductive surgery (CRS) to treat patients with colorectal cancer and peritoneal metastases (PM). In recent years, three randomized controlled trials
Beatrice J. Sun, Sara K. Daniel, Byrne Lee   +2 more
semanticscholar   +1 more source

Anastomosis versus rectal stump procedure in cytoreductive surgery with hyperthermic intraperitoneal chemotherapy for colorectal and appendiceal peritoneal metastases: A comparative study. [PDF]

Colorectal Dis
Abstract Aim Cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) is the standard treatment for peritoneal metastases (PM) of colorectal or appendiceal origin. Rectal anastomotic leakage (RAL) or rectal stump blow‐out is a serious complication following rectal resection after CRS‐HIPEC. This study aimed to compare outcomes
Ghanipour L, Mahmmud LO, Cashin P, Palmer GJ, Abraham-Nordling M.   +4 more
europepmc   +2 more sources

Current role for cytoreduction and HIPEC for gastric cancer with peritoneal disease

Journal of Surgical Oncology, 2022
Gastric cancer (GC) is an aggressive malignancy with a high burden of peritoneal disease. Evidence regarding the use of cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) to improve outcomes has been growing. However, given
H. Khan, F. Johnston
semanticscholar   +1 more source

Effect of HIPEC according to HRD/BRCAwt genomic profile in stage III ovarian cancer: Results from the phase III OVHIPEC trial

International Journal of Cancer, 2022
The addition of hyperthermic intraperitoneal chemotherapy (HIPEC) with cisplatin to interval cytoreductive surgery improves recurrence‐free (RFS) and overall survival (OS) in patients with stage III ovarian cancer. Homologous recombination deficient (HRD)
S. Koole, P. Schouten, J. Hauke, R. J. Kluin, P. Nederlof, Lisa Richters, Gabriele Krebsbach, K. Sikorska, M. Alkemade, M. Opdam, J. H. Schagen van Leeuwen, H. Schreuder, R. Hermans, I. D. de Hingh, C. Mom, H. Arts, M. van Ham, P. V. van Dam, P. Vuylsteke, J. Sanders, H. Horlings, K. K. van de Vijver, E. Hahnen, W. V. van Driel, R. Schmutzler, G. Sonke, S. Linn   +26 more
semanticscholar   +1 more source

Hyperthermic intraperitoneal chemotherapy for patients with gastric cancer based on laboratory tests is safe: a single Chinese center analysis

BMC Surgery, 2022
Purpose About 15%—40% of gastric cancer patients have peritoneal metastasis, which leads to poor prognosis. Hyperthermic intraperitoneal chemotherapy (HIPEC) is considered to be an effective treatment for these patients. This study evaluated the efficacy
Yunzi Wu, Xiaohao Zheng, Chunyang Sun, Shenghui Wang, Shikang Ding, Ming Wu, Jing Zhang, Bingzhi Wang, Liyan Xue, Lin Yang, Yantao Tian, Yibin Xie   +11 more
doaj   +1 more source