Results 31 to 40 of about 11,686 (228)

Adjuvant hyperthermic intraperitoneal chemotherapy (HIPEC) in patients with colon cancer at high risk of peritoneal carcinomatosis; the COLOPEC randomized multicentre trial [PDF]

, 2015
Background: The peritoneum is the second most common site of recurrence in colorectal cancer. Early detection of peritoneal carcinomatosis (PC) by imaging is difficult.
Aalbers, A.G.J. (Arend), Bemelman, W.A. (Willem), Boerma, D. (Djamila), Bremers, A.J.A. (Andreas), Burger, J.W.A. (Jacobus), Buskens, C.J. (Christianne), Dijkgraaf, M.G.W. (Marcel), Evers, P. (Pauline), Grevenstein, H.M.U. (Helma) van, Hemmer, P.H.J. (Patrick H.J.), Hingh, I.H.J.T. (Ignace) de, Klaver, C.E.L. (Charlotte), Lammers, L.A. (Laureen), Leeuwen, B.L. (B.) van, Meijerink, W.J.H.J. (Jeroen), Musters, G.D. (Gijsbert), Nienhuijs, S.W. (Simon), Pon, J. (Jolien), Punt, C.J.A. (Cornelis), Radema, S.A. (Sandra A.), Ramshorst, B. (Bert) van, Snaebjornsson, P., Tanis, P.J. (Pieter), te Velde, E.A. (Elisabeth A.), Tuynman, J.B., van der Bilt, J.D.W. (Jarmila D.W.), van Ginkel, R.J. (Robert J.), Verwaal, V.J. (Vic J.), Wiezer, M.J. (Marinus), Wilt, J.H.W. (Johannes) de   +29 more
core   +4 more sources

A Retrospective Observational Study of Hyperthermic Intraperitoneal Chemotherapy for Gastric Cancer and Colorectal Cancer From a Single Center in the Recent 5 years

Cancer Control
Objective To retrospectively analyze the effect of hyperthermic intraperitoneal chemotherapy (HIPEC) on the progression free survival (PFS) of advanced gastric cancer (GC) and colorectal cancer (CRC).
Miao He, Xiao-dong Li, Zi-wei Wang, Hao Sun, Jing Fan   +4 more
doaj   +1 more source

A human ex vivo coculture model to investigate peritoneal metastasis and innovative treatment options

Pleura and Peritoneum, 2021
Peritoneal metastasis (PM) is commonly observed in patients with colorectal cancer (CRC). The outcome of these patients is poor, with an average survival of only six months without therapy, which requires a better understanding of PM biology and new ...
Mönch Dina, Koch Jana, Maaß Annika, Janssen Nicole, Mürdter Thomas, Renner Philipp, Fallier-Becker Petra, Solaß Wiebke, Schwab Matthias, Dahlke Marc-H., Schlitt Hans J., Leibold Tobias   +11 more
doaj   +1 more source

Preclinical evaluation of local prolonged release of paclitaxel from gelatin microspheres for the prevention of recurrence of peritoneal carcinomatosis in advanced ovarian cancer [PDF]

, 2019
Patients with advanced ovarian cancer develop recurrence despite initial treatment response to standard treatment of surgery and intravenous/intraperitoneal (IP) chemotherapy, partly due to a limited peritoneal exposure time of chemotherapeutics ...
Ceelen, Wim, De Clercq, Kaat, De Wever, Olivier, Descamps, Benedicte, Hoorens, Anne, Vermeulen, An, Vervaet, Chris, Xie, Feifan   +7 more
core   +2 more sources

Therapeutic Applications of Stimuli‐Based Release and Engineering of Extracellular Vesicles

Advanced NanoBiomed Research, EarlyView.
This review summarizes the effects of endogenous and exogenous stimuli, their effects on the natural release of extracellular vesicles, as well as their uptake and release. It also gives an overview of stimuli‐responsive EVs and their therapeutic applications. Extracellular vesicles (EVs), nano‐ to microsized lipid bilayer membrane‐bound particles, are
Gloria Kemunto, Kristen Dellinger
wiley   +1 more source

Feasibility and Safety of Pressurized Intraperitoneal Aerosol Chemotherapy for Peritoneal Carcinomatosis: A Retrospective Cohort Study. [PDF]

, 2017
Background. Pressurized intraperitoneal aerosol chemotherapy (PIPAC) has been introduced as a novel repeatable treatment for peritoneal carcinomatosis.
Demartines, N., Grass, F., Hahnloser, D., Hübner, M., Mathevet, P., Teixeira Farinha, H., Wolfer, A.   +6 more
core   +8 more sources

Efficacy analysis of prophylactic hyperthermic intraperitoneal chemotherapy in patients with locally advanced gastric cancer: a retrospective study

Frontiers in Oncology
PurposeThis study aims to evaluate the effectiveness and safety of prophylactic hyperthermic intraperitoneal chemotherapy (P-HIPEC) in patients with locally advanced gastric cancer (AGC) after laparoscopic radical gastrectomy.
Zhijie Gong, Zhijie Gong, Liping Zhou, Yinghao He, Yinghao He, Jun Zhou, Yanjie Deng, Zudong Huang, WeiWei Wang, Qiangbang Yang, Jian Pan, Yingze Li, Xiaolu Yuan, Minghui Ma   +13 more
doaj   +1 more source

Effect of hyperthermia on improving neutrophil restoration after intraperitoneal chemotherapy

International Journal of Hyperthermia, 2019
Purpose: Intraperitoneal (IP) chemotherapy has several benefits but also can have severe hematologic side effects. We compared the effects of hyperthermic intraperitoneal chemotherapy (HIPEC) and conventional IP chemotherapy on bone marrow suppression ...
Wan-Chun Huang, Chao-Chih Wu, Yun-Ting Hsu, Chih-Long Chang   +3 more
doaj   +1 more source

Tumor Mutational Burden Associated With Response to Hyperthermic Intraperitoneal Chemotherapy

Frontiers in Oncology, 2022
BackgroundGastric cancer (GC) is one of the most common cancer types, especially in Asian countries. Hyperthermic intraperitoneal chemotherapy (HIPEC) has been shown to improve the progression-free survival among gastric cancer patients with peritoneal ...
Lisi Zeng, Xubo Huang, Yun Tian, Jinxia Huang, Huiyan Liu, Juncai Wen, Kaihua Liu, Yang Shao, Jiali Luo, Hongsheng Tang, Quanxing Liao, Ziying Lei, Weiwen Cui, Qianghua Xia, Tianpei Guan, Jin Li, Shuzhong Cui, Shuzhong Cui   +17 more
doaj   +1 more source

Treatments and overall survival in patients with Krukenberg tumor [PDF]

, 2019
BACKGROUND: Krukenberg tumor (KT) is a rare secondary ovarian tumor, primarily localized at the gastrointestinal tract in most cases. KT is related to severe prognosis due to its aggressiveness, diagnostic difficulties and poor treatment efficacy ...
Corcione, Francesco, D'Armiento, Maria, De Luca, Marcello, Insabato, Luigi, Lionetti, Ruggero, Mascolo, Massimo, Raffone, Antonio, Saccone, Gabriele, Travaglino, Antonio, Zullo, Fulvio   +9 more
core   +1 more source